Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

32 questions · 41 findings · 3 reviews · Pregnancy and Childbirth

No studies found 0 · 0%GRADE not reported 3 · 7.3%Very low 17 · 41.5%Low 16 · 39%Moderate 4 · 9.8%High 1 · 2.4%

Combined spinal‐epidural vs high‐dose spinal

Number of women requiring a repeat regional block or a general anaesthetic as a result of failure to establish adequate initial blockade · women undergoing caesarean section

Combined spinal‐epidural showed no clear difference in number of women requiring a repeat regional block or a general… compared with high‐dose spinal (low certainty).

1 finding from 1 review

Combined spinal‐epidural vs low‐dose spinal

Number of women requiring a repeat regional block or a general anaesthetic as a result of failure to establish adequate initial blockade · women undergoing caesarean section

Combined spinal‐epidural showed no clear difference in number of women requiring a repeat regional block or a general… compared with low‐dose spinal (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Nausea · preventing nausea and vomiting

It is very uncertain whether antihistamines changes nausea ‐ intraoperative compared with placebo (very low certainty).

2 findings from 1 review

Opioid antagonists vs placebo

Nausea · preventing nausea and vomiting
2 findings from 1 review

Ginger vs placebo

Nausea · preventing nausea and vomiting

It is very uncertain whether ginger changes nausea ‐ intraoperative compared with placebo (very low certainty).

2 findings from 1 review