Findings

What do systematic reviews say?

226 questions · 228 findings · 28 reviews · Musculoskeletal

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No studies found 73 · 32%GRADE not reported 6 · 2.6%Very low 37 · 16.2%Low 70 · 30.7%Moderate 22 · 9.6%High 20 · 8.8%

Preoperative education vs usual care

Pain WOMAC pain. Scale from: 0 to 100 (lower scores indicate less pain). · patients with knee replacement surgery

1 finding from 1 review

Preoperative education for hip or knee replacement 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 109 participants
Low

Preoperative education vs usual care

Functional ability · patients with knee replacement surgery

1 finding from 1 review

Preoperative education for hip or knee replacement 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 109 participants
Low

Tricyclic antidepressants vs control

Pain < 1 week VAS scale 0 to 100 mm · patients with pain management in rheumatoid arthritis

1 finding from 1 review

Antidepressants for pain management in rheumatoid arthritis 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Tricyclic antidepressants vs control

Pain 1 to 6 weeks Any pain measurement scale · patients with pain management in rheumatoid arthritis

1 finding from 1 review

Antidepressants for pain management in rheumatoid arthritis 2011 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 482 participants
Very low

Tricyclic antidepressants vs control

Pain > 6 weeks Any pain measurement scale · patients with pain management in rheumatoid arthritis

1 finding from 1 review

Antidepressants for pain management in rheumatoid arthritis 2011 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 368 participants
Very low

Tricyclic antidepressants vs control

Functional Status Health Assessment Questionnaire (HAQ) scale 0 to 3 · patients with pain management in rheumatoid arthritis

1 finding from 1 review

Antidepressants for pain management in rheumatoid arthritis 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Low

Tricyclic antidepressants vs control

Withdrawals due to adverse events · patients with pain management in rheumatoid arthritis

It is very uncertain whether tricyclic antidepressant changes number of Withdrawals due to Adverse Events patient interview compared with control (very low certainty).

1 finding from 1 review

Antidepressants for pain management in rheumatoid arthritis 2011 · Cochrane Headline outcomes only
RR 0.98 [0.59, 1.64]
6 studies · 455 participants
Very low

Tricyclic antidepressants vs control

Total number of adverse events patient interview · patients with pain management in rheumatoid arthritis

It is very uncertain whether tricyclic antidepressant changes total number of adverse events patient interview compared with control (very low certainty).

1 finding from 1 review

Antidepressants for pain management in rheumatoid arthritis 2011 · Cochrane Headline outcomes only
RR 1.83 [1.01, 3.3]
6 studies · 455 participants
Very low

Subacromial decompression vs Placebo (sham/placebo device)

Paina (scale from 0‐10, 0 is no pain) · people with impingement syndrome without full‐thickness rotator cuff tears

1 finding from 1 review

Subacromial decompression surgery for rotator cuff disease 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 284 participants
High

Subacromial decompression vs exercise

QoL · people with impingement syndrome without full‐thickness rotator cuff tears

1 finding from 1 review

Subacromial decompression surgery for rotator cuff disease 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 116 participants
Low

Subacromial decompression vs exercise

Adverse events · people with impingement syndrome without full‐thickness rotator cuff tears

Subacromial decompression showed no clear difference in adverse events compared with exercises (moderate certainty).

1 finding from 1 review

Subacromial decompression surgery for rotator cuff disease 2019 · Cochrane Headline outcomes only
RR 0.91 [0.31, 2.65]
2 studies · 406 participants
Moderate

Subacromial decompression vs exercise

Serious adverse events · people with impingement syndrome without full‐thickness rotator cuff tears

1 finding from 1 review

Subacromial decompression surgery for rotator cuff disease 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Subacromial decompression vs Placebo (sham/placebo device)

Functional outcomes · people with impingement syndrome without full‐thickness rotator cuff tears

1 finding from 1 review

Subacromial decompression surgery for rotator cuff disease 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 274 participants
High

Subacromial decompression vs Placebo (sham/placebo device)

Global assessment of treatment success · people with impingement syndrome without full‐thickness rotator cuff tears

Subacromial decompression showed no clear difference in global assessment of treatment success compared with placebo surgery (moderate certainty).

1 finding from 1 review

Subacromial decompression surgery for rotator cuff disease 2019 · Cochrane Headline outcomes only
RR 1.08 [0.93, 1.27]
2 studies · 290 participants
Moderate

Subacromial decompression vs Placebo (sham/placebo device)

Health status and quality of life · people with impingement syndrome without full‐thickness rotator cuff tears

1 finding from 1 review

Subacromial decompression surgery for rotator cuff disease 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 285 participants
High

Subacromial decompression vs Placebo (sham/placebo device)

Adverse events · people with impingement syndrome without full‐thickness rotator cuff tears

Subacromial decompression showed no clear difference in adverse events compared with placebo surgery (moderate certainty).

1 finding from 1 review

Subacromial decompression surgery for rotator cuff disease 2019 · Cochrane Headline outcomes only
RR 0.91 [0.31, 2.65]
2 studies · 406 participants
Moderate

Subacromial decompression vs Placebo (sham/placebo device)

Serious adverse events · people with impingement syndrome without full‐thickness rotator cuff tears

1 finding from 1 review

Subacromial decompression surgery for rotator cuff disease 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 331 participants
Moderate

Subacromial decompression vs exercise

Paina (scale from 0‐10, 0 is no pain) · people with impingement syndrome without full‐thickness rotator cuff tears

1 finding from 1 review

Subacromial decompression surgery for rotator cuff disease 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 316 participants
Low

Subacromial decompression vs exercise

Functional outcomes · people with impingement syndrome without full‐thickness rotator cuff tears

1 finding from 1 review

Subacromial decompression surgery for rotator cuff disease 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 259 participants
Low

Subacromial decompression vs exercise

Global assessment of treatment success · people with impingement syndrome without full‐thickness rotator cuff tears

Subacromial decompression showed no clear difference in global assessment of treatment success compared with exercises (low certainty).

1 finding from 1 review

Subacromial decompression surgery for rotator cuff disease 2019 · Cochrane Headline outcomes only
RR 1.21 [0.96, 1.51]
2 studies · 158 participants
Low