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Evidence found and GRADE certainty

152 questions · 166 findings · 8 reviews · Stroke

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No studies found 63 · 38%GRADE not reported 20 · 12%Very low 66 · 39.8%Low 17 · 10.2%Moderate 0 · 0%High 0 · 0%

Non‐pharmaceutical interventions vs placebo/usual care or different forms of intervention

Psychological well‐being (secondary outcome) Not addressed · people within 3 months after stroke
2 findings from 1 review

Pharmacological interventions vs placebo

Depression: meeting study criteria for depression at end of · people with depression after stroke

It is very uncertain whether pharmacological interventions changes depression: meeting study criteria for depression at end of… compared with placebo (very low certainty).

2 findings from 1 review

Pharmacological interventions vs placebo

Depression: < 50% reduction in scale scores at end of treatment (primary outcome) · people with depression after stroke

It is very uncertain whether pharmacological interventions changes depression: < 50% reduction in scale scores at end of treatment… compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Adverse events: death ‐ at end of treatment (secondary outcome) · people with depression after stroke

It is very uncertain whether pharmacological interventions changes adverse events: death (secondary outcome) compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Adverse effects (central nervous system) · people with depression after stroke

It is very uncertain whether pharmacological interventions changes adverse events: all ‐ central nervous system events (e.g. confusion,… compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Gastrointestinal adverse events · people with depression after stroke

It is very uncertain whether pharmacological interventions changes adverse events: all ‐ gastrointestinal effects (e.g. constipation,… compared with placebo (very low certainty).

1 finding from 1 review

Visual interventions vs control

Activities of daily living · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether visual interventions changes activities of daily living: effects persisting at least 1 month post… compared with any control (very low certainty).

2 findings from 1 review

Visual interventions vs control

Neglect outcomes: effects persisting at least 1 month post intervention · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether visual interventions changes neglect outcomes: effects persisting at least 1 month post… compared with any control (very low certainty).

1 finding from 1 review

Movement interventions vs control

Activities of daily living · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

The review found no eligible studies for this question.

2 findings from 1 review

Movement interventions vs control

Neglect outcomes: effects persisting at least 1 month post intervention · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

The review found no eligible studies for this question.

1 finding from 1 review

Antidepressants vs placebo

Depression: meeting study criteria for depression at end of · people with stroke

It is very uncertain whether pharmacological interventions (antidepressants) changes depression: meeting study criteria for depression at end treatment… compared with placebo (very low certainty).

1 finding from 1 review