Serious adverse events: number experiencing 24 weeks · Patients with osteoarthritis of the knee or hip
Paracetamol showed no clear difference in serious adverse events: number experiencing 24 weeks compared with placebo (moderate certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Patients with acute low‐back pain
2 findings from 1 review
Disability 1 week (immediate term) (RMDQ 0 to 24) · Patients with acute low‐back pain
2 findings from 1 review
Any adverse events Up to 12 weeks' · Patients with acute low‐back pain
Paracetamol showed no clear difference in any adverse events Up to 12 weeks' compared with placebo (high certainty).
1 finding from 1 review
Serious adverse events Up to 12 weeks' · Patients with acute low‐back pain
Paracetamol showed no clear difference in serious adverse events Up to 12 weeks' compared with placebo (moderate certainty).
1 finding from 1 review
Relief of pain · women who have given birth vaginally, requiring analgesia for after‐birth pains.
It is very uncertain whether paracetamol changes adequate pain relief as reported by the woman (6 hours) compared with placebo (very low certainty).
1 finding from 1 review
Need for additional pain relief (up to 4 hours) · women who have given birth vaginally, requiring analgesia for after‐birth pains.
It is very uncertain whether paracetamol changes need for additional pain relief (up to 4 hours) compared with placebo (very low certainty).
1 finding from 1 review
Maternal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.
It is very uncertain whether paracetamol changes maternal adverse events (up to 4 hours and at 6 hours) compared with placebo (very low certainty).
1 finding from 1 review
Neonatal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Length of hospital stay · women who have given birth vaginally, requiring analgesia for after‐birth pains.
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Any breastfeeding at hospital discharge · women who have given birth vaginally, requiring analgesia for after‐birth pains.
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Any breastfeeding at 6 weeks postpartum · women who have given birth vaginally, requiring analgesia for after‐birth pains.
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Relief of pain · women who have given birth vaginally, requiring analgesia for after‐birth pains.
It is very uncertain whether paracetamol changes adequate pain relief as reported by the woman (6 hours) compared with NSAID (very low certainty).
1 finding from 1 review
Additional analgesia required (escape analgesia) · women who have given birth vaginally, requiring analgesia for after‐birth pains.
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Maternal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.
It is very uncertain whether paracetamol changes maternal adverse events (up to 4 hours and at 6 hours) compared with NSAID (very low certainty).
1 finding from 1 review
Neonatal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Length of hospital stay · women who have given birth vaginally, requiring analgesia for after‐birth pains.
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Any breastfeeding at hospital discharge · women who have given birth vaginally, requiring analgesia for after‐birth pains.
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Any breastfeeding at 6 weeks postpartum · women who have given birth vaginally, requiring analgesia for after‐birth pains.
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Failure of PDA closure after first course of treatment (assessed by post‐treatment ECHO) · preterm or low birth weight infants with PDA
Late paracetamol showed no clear difference in failure of PDA closure after first course of treatment (assessed by… compared with placebo/no intervention (low certainty).
1 finding from 1 review