Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

323 questions · 366 findings · 43 reviews

No studies found 135 · 36.9%GRADE not reported 40 · 10.9%Very low 85 · 23.2%Low 65 · 17.8%Moderate 38 · 10.4%High 3 · 0.8%

Open surgery by transverse incision of the skin in the distal palmar crease vs open surgery

Neurovascular injury Not measured · patients with trigger finger

The review found no eligible studies for this question.

3 findings from 1 review

Open surgery vs ERCP

Retained stones after primary intervention · with common bile duct stones

Open surgery probably leads to lower retained stones after primary intervention compared with ERCP (moderate certainty).

1 finding from 1 review

Surgery plus Heister jaw opener vs Surgery plus wooden tongue depressors

Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)

It is very uncertain whether surgery plus Heister jaw opener changes maximal mouth opening (interincisal distance) compared with surgery plus wooden tongue depressors (very low certainty).

2 findings from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Proportion of participants who required further glaucoma surgery, including laser · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

Cataract surgery with Hydrus microstent may leads to lower proportion of participants who required further glaucoma surgery,… compared with cataract surgery alone (low certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Proportion of participants who required further glaucoma surgery, including laser · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in proportion of participants who required further glaucoma surgeryat… compared with phacoemulsification alone (low certainty).

1 finding from 1 review

Prosthetic mesh placement vs usual care

Subgroup analysis:Incidence of parastomal hernia (open surgery) ( · individuals having a stoma formation

Prosthetic mesh placement probably leads to lower subgroup analysis:Incidence of parastomal hernia (open surgery) ( compared with standard treatment (moderate certainty).

1 finding from 1 review

Surgery plus Heister jaw opener vs Surgery plus wooden tongue depressors

Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
1 finding from 1 review
  • Vadepally 2019 measured burning sensation on a VAS but did not fully report results, stating there was no significant difference between the 2 groups (p=0.617).
    1 study · 50 participants
    GRADE not reported

Cataract surgery with Hydrus microstent vs cataract surgery alone

Proportion of participants who were medication‐free (not using eye drops) medium‐term · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

Cataract surgery with Hydrus microstent probably leads to higher proportion of participants who were medication‐free (not using eye… compared with cataract surgery alone (moderate certainty).

1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Mean change in unmedicated IOP (after washout) measured using Goldmann applanation tonometry medium‐term · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Glaucoma progression at 12 months, measured by additional visual field defects · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Mean change in health‐related quality of life · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review

Endoscopic surgery vs open surgery

Resolution of symptoms · patients with trigger finger

It is very uncertain whether endoscopic surgery changes resolution of symptoms compared with open surgery (very low certainty).

1 finding from 1 review