Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

111 questions · 123 findings · 10 reviews · Gynaecology and Fertility

No studies found 21 · 17.1%GRADE not reported 1 · 0.8%Very low 34 · 27.6%Low 49 · 39.8%Moderate 18 · 14.6%High 0 · 0%

Oestrogen vs no pretreatment

Live birth or ongoing pregnancy · ovarian stimulation protocols for women undergoing ART

Oestrogen showed no clear difference in live birth or ongoing pregnancy (Oestr + Ant vs Ant) compared with no pretreatment (moderate certainty).

2 findings from 1 review

Oestrogen vs no pretreatment

Pregnancy loss · ovarian stimulation protocols for women undergoing ART

It is very uncertain whether oestrogen changes pregnancy loss (Oestr + Ant vs Ant) compared with no pretreatment (very low certainty).

2 findings from 1 review

Oestrogen vs no pretreatment

Multiple pregnancy rate · ovarian stimulation protocols for women undergoing ART

The review found no eligible studies for this question.

2 findings from 1 review

Dose comparison: oestrogen 100 µg patch vs 200 µg patch plus progestogen

Adverse events ‐ specific side effects attributed to oestrogen over 8 months' · women with PMS

It is very uncertain whether dose comparison: oestrogen 100 µg patch changes adverse events ‐ specific side effects attributed to oestrogen over… compared with 200 µg patch plus progestogen (very low certainty).

1 finding from 1 review

Antioestrogen plus medical adjunct vs antioestrogen

Clinical pregnancy · ovulation induction in polycystic ovarian syndrome

Antioestrogen plus medical adjunct showed no clear difference in clomiphene citrate plus bromocriptine versus clomiphene citrate ‐… compared with antioestrogen alone (low certainty).

1 finding from 1 review