It is very uncertain whether myomectomy changes miscarriage Rate ‐ Submucous compared with no treatment (very low certainty).
It is very uncertain whether laparoscopic myomectomy changes live birth rate compared with myomectomy by laparotomy or mini‐laparotomy (very low certainty).
It is very uncertain whether laparoscopic myomectomy changes preterm delivery rate compared with myomectomy by laparotomy or mini‐laparotomy (very low certainty).
It is very uncertain whether laparoscopic myomectomy changes clinical pregnancy rate compared with myomectomy by laparotomy or mini‐laparotomy (very low certainty).
It is very uncertain whether laparoscopic myomectomy changes ongoing pregnancy rate compared with myomectomy by laparotomy or mini‐laparotomy (very low certainty).
It is very uncertain whether laparoscopic myomectomy changes miscarriage Rate compared with myomectomy by laparotomy or mini‐laparotomy (very low certainty).
It is very uncertain whether laparoscopic myomectomy changes caesarean section rate compared with myomectomy by laparotomy or mini‐laparotomy (very low certainty).
Misoprostol showed no clear difference in blood loss (ml) Estimated blood loss during myomectomy compared with placebo to reduce blood loss during myomectomy (moderate certainty).
Vasopressin showed no clear difference in blood loss (ml) Estimated blood loss during myomectomy compared with placebo to reduce blood loss during myomectomy (moderate certainty).
Bupivicaine plus epinephrine showed no clear difference in blood loss (ml) Estimated blood loss during myomectomy compared with placebo to reduce blood loss during myomectomy (low certainty).
Peri‐cervical tourniquet showed no clear difference in blood loss (ml) Estimated blood loss during myomectomy compared with no treatment to reduce blood loss during myomectomy (low certainty).
Gelatin‐thrombin matrix showed no clear difference in blood loss (ml) Estimated blood loss during myomectomy compared with placebo or no treatment to reduce blood loss during myomectomy (low certainty).
Ascorbic acid showed no clear difference in blood loss (ml) Estimated blood loss during myomectomy compared with no treatment to reduce blood loss during myomectomy (low certainty).
The review found no eligible studies for this question.
Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in loop ligation of myoma pseudocapsule plus vasopressin compared with placebo or no treatment (low certainty).
Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in fibrin sealant patch (collagen sponge with thrombin and fibrinogen) compared with placebo or no treatment (low certainty).
Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in vasopressin compared with placebo or no treatment (moderate certainty).
Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in bupivicaine plus epinephrine compared with placebo or no treatment (low certainty).
Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in intravenous injection of tranexamic acid compared with placebo or no treatment (low certainty).
Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in gelatin‐thrombin matrix compared with placebo or no treatment (low certainty).