Cochrane · systematic review · CD003857
Surgical treatment of fibroids for subfertility
Metwally, M, Raybould, G, Cheong, YC, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
23
current version
GRADE rated
17
No studies
6
Included studies
NR
No studies 6 · 26.1%Ungraded 0 · 0%Very low 17 · 73.9%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsMyomectomy compared to no treatment for fibroids for infertility
Population: fibroids for infertility
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth rate Myomectomy vs no treatment | no estimate extracted | NR | No studies |
Preterm delivery rate Myomectomy vs no treatment | no estimate extracted | NR | No studies |
Clinical pregnancy rate ‐ Intramural Myomectomy vs no treatment | OR 1.88 [0.57, 6.14] | 1 study · 45 participants | Very low Downgraded: indirectness |
Clinical pregnancy rate ‐ Submucous Myomectomy vs no treatment | OR 2.04 [0.62, 6.66] | 1 study · 52 participants | Very low Downgraded: indirectness |
Clinical pregnancy rate ‐ Intramural/Subserous Myomectomy vs no treatment | OR 2 [0.4, 10.09] | 1 study · 31 participants | Very low Downgraded: indirectness |
Clinical pregnancy rate ‐ Intramural/Submucous Myomectomy vs no treatment | OR 3.24 [0.72, 14.57] | 1 study · 42 participants | Very low Downgraded: indirectness |
Ongoing pregnancy rate Myomectomy vs no treatment | no estimate extracted | NR | No studies |
Miscarriage Rate ‐ Intramural Myomectomy vs no treatment | OR 1.33 [0.26, 6.78] | 1 study · 45 participants | Very low Downgraded: indirectness |
Miscarriage Rate ‐ Submucous Myomectomy vs no treatment | OR 1.27 [0.27, 5.97] | 1 study · 52 participants | Very low Downgraded: indirectness |
Miscarriage Rate ‐ Intramural/Subserous Myomectomy vs no treatment | OR 0.8 [0.1, 6.54] | 1 study · 31 participants | Very low Downgraded: indirectness |
Miscarriage Rate ‐ Intramural/Submucous Myomectomy vs no treatment | OR 2 [0.32, 12.33] | 1 study · 42 participants | Very low Downgraded: indirectness |
Caesarean section rate Myomectomy vs no treatment | no estimate extracted | NR | No studies |
Laparoscopic myomectomy compared to myomectomy by laparotomy or mini‐laparotomy for fibroids for infertility
Population: fibroids for infertility
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth rate Laparoscopic myomectomy vs myomectomy by laparotomy or mini‐laparotomy | OR 0.8 [0.42, 1.5] | 2 studies · 177 participants | Very low Downgraded: imprecision, indirectness |
Preterm delivery rate Laparoscopic myomectomy vs myomectomy by laparotomy or mini‐laparotomy | OR 0.7 [0.11, 4.29] | 2 studies · 177 participants | Very low Downgraded: imprecision, indirectness |
Clinical pregnancy rate Laparoscopic myomectomy vs myomectomy by laparotomy or mini‐laparotomy | OR 0.96 [0.52, 1.78] | 2 studies · 177 participants | Very low Downgraded: imprecision, indirectness |
Ongoing pregnancy rate Laparoscopic myomectomy vs myomectomy by laparotomy or mini‐laparotomy | OR 1.61 [0.26, 10.04] | 1 study · 115 participants | Very low Downgraded: imprecision, indirectness |
Miscarriage Rate Laparoscopic myomectomy vs myomectomy by laparotomy or mini‐laparotomy | OR 1.25 [0.4, 3.89] | 2 studies · 177 participants | Very low Downgraded: imprecision, indirectness |
Caesarean section rate Laparoscopic myomectomy vs myomectomy by laparotomy or mini‐laparotomy | OR 0.69 [0.34, 1.39] | 2 studies · 177 participants | Very low Downgraded: imprecision, inconsistency, indirectness |
Monopolar resectoscope compared to bipolar resectoscope for hysteroscopic myomectomy for infertility
Population: hysteroscopic myomectomy for infertility
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth rate/ ongoing pregnancy ratea Monopolar resectoscope vs bipolar resectoscope | OR 0.86 [0.3, 2.5] | 1 study · 68 participants | Very low Downgraded: imprecision |
Preterm delivery rate Monopolar resectoscope vs bipolar resectoscope | no estimate extracted | NR | No studies |
Clinical pregnancy rate Monopolar resectoscope vs bipolar resectoscope | OR 0.88 [0.33, 2.36] | 1 study · 68 participants | Very low Downgraded: imprecision |
Miscarriage rate Monopolar resectoscope vs bipolar resectoscope | OR 1 [0.19, 5.34] | 1 study · 68 participants | Very low Downgraded: imprecision |
Caesarean section rate Monopolar resectoscope vs bipolar resectoscope | no estimate extracted | NR | No studies |