Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

68 questions · 68 findings · 3 reviews

No studies found 18 · 26.5%GRADE not reported 0 · 0%Very low 2 · 2.9%Low 29 · 42.6%Moderate 16 · 23.5%High 3 · 4.4%

Urea‐containing moisturisers vs vehicle, placebo or no moisturiser

Change from baseline in disease severity as assessed by the participants (number of participants who considered their skin to have improved) · people with eczema

Urea‐containing moisturisers may leads to higher change from baseline in disease severity according to the… compared with vehicle, placebo or no moisturiser (low certainty).

1 finding from 1 review

Urea‐containing moisturisers vs vehicle, placebo or no moisturiser

Change from baseline in disease severity according to the investigators (number of participants who improved according to the investigators) · people with eczema

Urea‐containing moisturisers probably leads to higher change from baseline in disease severity according to the… compared with vehicle, placebo or no moisturiser (moderate certainty).

1 finding from 1 review

Glycerin/glycerol‐containing moisturisers vs vehicle or placebo

Change from baseline in disease severity as assessed by the participants(number of participants who considered their dry skin to have improved) · people with eczema

Glycerin/glycerol‐containing moisturisers probably leads to higher change from baseline in disease severity as assessed by the… compared with vehicle or placebo (moderate certainty).

1 finding from 1 review

Barrier creams and moisturisers vs no treatment

The proportion of participants developing any signs and symptoms of OIHD (incident cases) measured by clinical scores (IGA) or hand dermatitis scores (e.g. HECSI, Manuscore), or both, as rated by the investigator (physician/nurse) or the participa... · workers at risk of occupational irritant hand dermatitis

Barrier creams and moisturisers showed no clear difference in the proportion of participants developing any signs and symptoms of… compared with no treatment (low certainty).

1 finding from 1 review

Skin care intervention vs standard skin care or no skin care intervention

Stinging/allergic reactions to moisturisers (over the intervention period) · infants

Skin care intervention showed no clear difference in stinging/allergic reactions to moisturisers (over the intervention… compared with standard skin care or no skin care intervention (low certainty).

1 finding from 1 review