Ovulation rate per woman fParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome
Metformin may leads to lower ovulation rate per woman fParticipants with BMI ≥ 30 kg/m2 compared with clomiphene citrate (low certainty).
Hirsutism ‐ Clinical F‐G score · adult women with PCOS
1 finding from 1 review
Hirsutism ‐ Clinical F‐G score · adolescent women with PCOS
1 finding from 1 review
Adverse events ‐ Severe · adult women with PCOS
Metformin may leads to higher adverse events ‐ Severe compared with oral contraceptive pill (OCP) (low certainty).
1 finding from 1 review
Adverse event ‐ Severe · adolescent women with PCOS
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Minor adverse events · adolescent women with PCOS
It is very uncertain whether metformin changes adverse event ‐ Minor compared with oral contraceptive pill (OCP) (very low certainty).
1 finding from 1 review
Improved menstrual pattern · adolescent women with PCOS
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acne ‐ Visual analogue scale or Clinical acne score · adolescent women with PCOS
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Body‐mass index (BMI) · adolescent women with PCOS
1 finding from 1 review
Minor adverse events · adult women with PCOS
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Improved menstrual pattern · adult women with PCOS
1 finding from 1 review
Acne ‐ Visual analogue scale or Clinical acne score · adult women with PCOS
1 finding from 1 review
Body‐mass index (BMI) · adult women with PCOS
1 finding from 1 review
Live birth rate per woman ‐ long protocol GnRH‐agonist · women with polycystic ovary syndrome
Metformin showed no clear difference in live birth rate per woman ‐ long protocol GnRH‐agonist compared with placebo or no treatment (low certainty).
1 finding from 1 review
Live birth rate per woman ‐ short protocol GnRH‐antagonist · women with polycystic ovary syndrome
Metformin may leads to lower live birth rate per woman ‐ short protocol GnRH‐antagonist compared with placebo or no treatment (low certainty).
1 finding from 1 review
OHSS · women with polycystic ovary syndrome
Metformin may leads to lower incidence of OHSS per woman compared with placebo or no treatment (low certainty).
1 finding from 1 review
Clinical pregnancy rate per woman ‐ long protocol GnRH‐agonist · women with polycystic ovary syndrome
Metformin may leads to higher clinical pregnancy rate per woman ‐ long protocol GnRH‐agonist compared with placebo or no treatment (low certainty).
1 finding from 1 review
Side effects per woman · women with polycystic ovary syndrome
Metformin may leads to higher side effects per woman compared with placebo or no treatment (low certainty).
1 finding from 1 review
Live birth rate per woman · women with polycystic ovary syndrome
Metformin showed no clear difference in live birth rate per woman compared with placebo or no treatment (low certainty).
1 finding from 1 review
Miscarriage rate per woman aParticipants with BMI < 30 kg/2 · women with polycystic ovary syndrome
Metformin showed no clear difference in miscarriage rate per woman aParticipants with BMI < 30 kg/2 compared with clomiphene citrate (low certainty).
1 finding from 1 review