Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

145 questions · 160 findings · 10 reviews · All outcomes

No studies found 27 · 16.9%GRADE not reported 63 · 39.4%Very low 63 · 39.4%Low 2 · 1.3%Moderate 1 · 0.6%High 4 · 2.5%

Salvadora persica (miswak) mouthrinse vs Pre-treatment (baseline, same group)

Streptococcus mutans count · Medically healthy individuals (adults and children, 6-60 years)

Salvadora persica rinse reduced Streptococcus mutans counts relative to baseline; not GRADE-rated.

1 finding from 1 review

Salvadora persica (miswak) mouthrinse vs Placebo rinse

Streptococcus mutans count · Medically healthy individuals (adults and children, 6-60 years)

Salvadora persica rinse reduced Streptococcus mutans counts more than placebo (favours Salvadora persica); not GRADE-rated.

1 finding from 1 review

Salvadora persica (miswak) mouthrinse vs Placebo rinse

Plaque · Medically healthy individuals (adults and children, 6-60 years)

Salvadora persica rinse reduced plaque more than placebo (favours Salvadora persica); certainty not GRADE-rated (Shekelle grade Ia).

1 finding from 1 review

Chlorhexidine 0.12% mouthrinse vs Pre-treatment (baseline, same group)

Plaque · Medically healthy individuals (adults and children, 6-60 years)

0.12% chlorhexidine rinse reduced plaque relative to baseline; not GRADE-rated.

1 finding from 1 review

Salvadora persica (miswak) mouthrinse vs Pre-treatment (baseline, same group)

Plaque · Medically healthy individuals (adults and children, 6-60 years)

Salvadora persica rinse reduced plaque relative to its own baseline; not GRADE-rated.

1 finding from 1 review

Placebo rinse vs Pre-treatment (baseline, same group)

Streptococcus mutans count · Medically healthy individuals (adults and children, 6-60 years)

Placebo rinse did not significantly change Streptococcus mutans counts relative to baseline; not GRADE-rated.

1 finding from 1 review

Chlorhexidine 0.2% vs Pre-treatment (baseline, same group)

Plaque · Medically healthy individuals (adults and children, 6-60 years)

0.2% chlorhexidine rinse reduced plaque relative to baseline; not GRADE-rated.

1 finding from 1 review

Personalised one-to-one OHA vs Routine one-to-one OHA

Patient-reported changes in knowledge, attitudes and quality of life · Children or adults (fit and healthy, or with a well-defined medical condition)
1 finding from 1 review

Any form of one-to-one oral hygiene advice (OHA) vs No OHA

Dental caries · Children or adults (fit and healthy, or with a well-defined medical condition)

It is very uncertain whether any form of one-to-one oral hygiene advice (OHA) changes dental caries compared with no OHA (very low certainty).

1 finding from 1 review

Self-management (self-administered/self-monitored OHA) vs Professional OHA

Gingivitis · Children or adults (fit and healthy, or with a well-defined medical condition)

It is very uncertain whether self-management (self-administered/self-monitored OHA) changes periodontal health: gingivitis compared with professional OHA (very low certainty).

1 finding from 1 review

Any form of one-to-one oral hygiene advice (OHA) vs No OHA

Gingivitis · Children or adults (fit and healthy, or with a well-defined medical condition)

It is very uncertain whether any form of one-to-one oral hygiene advice (OHA) changes periodontal health: gingivitis compared with no OHA (very low certainty).

1 finding from 1 review

Personalised one-to-one OHA vs Routine one-to-one OHA

Patient-reported behaviour changes and health indices · Children or adults (fit and healthy, or with a well-defined medical condition)
1 finding from 1 review

Self-management (self-administered/self-monitored OHA) vs Professional OHA

Patient-reported behaviour changes · Children or adults (fit and healthy, or with a well-defined medical condition)
1 finding from 1 review

Personalised one-to-one OHA vs Routine one-to-one OHA

Gingivitis · Children or adults (fit and healthy, or with a well-defined medical condition)

It is very uncertain whether personalised one-to-one OHA changes periodontal health: gingivitis compared with routine one-to-one OHA (very low certainty).

1 finding from 1 review

Personalised one-to-one OHA vs Routine one-to-one OHA

Dental caries · Children or adults (fit and healthy, or with a well-defined medical condition)
1 finding from 1 review