Treatment failure · adults and adolescents with scrub typhus
It is very uncertain whether macrolides changes treatment failure compared with doxycycline (very low certainty).
1 finding from 1 review
Resolution of fever within 48 hours · adults and adolescents with scrub typhus
It is very uncertain whether macrolides changes resolution of fever within 48 hours compared with doxycycline (very low certainty).
1 finding from 1 review
Resolution of fever within 5 days · adults and adolescents with scrub typhus
Macrolides showed no clear difference in resolution of fever within 5 days compared with doxycycline (low certainty).
1 finding from 1 review
Time to defervescence · adults and adolescents with scrub typhus
1 finding from 1 review
Exacerbations (number of people experiencing ≥ 1 exacerbations) · adults with bronchiectasis
Macrolides probably leads to lower ≥ 1 exacerbation compared with placebo (moderate certainty).
1 finding from 1 review
All‐cause mortality · adults with bronchiectasis
1 finding from 1 review
SGRQ Total SGRQ (Total) Score. Scale from: 0 to 100. Lower score indicates better quality of life. · adults with bronchiectasis
1 finding from 1 review
Change in SGRQ total score · adults with bronchiectasis
1 finding from 1 review
Exacerbation frequency · children with bronchiectasis
Macrolides may leads to lower exacerbation frequency compared with placebo (low certainty).
1 finding from 1 review
Hospitalisation (any cause) · children with bronchiectasis
Macrolides showed no clear difference in hospitalisation: all‐cause compared with placebo (low certainty).
1 finding from 1 review
Serious adverse events · children with bronchiectasis
Macrolides showed no clear difference in serious adverse events compared with placebo (low certainty).
1 finding from 1 review
All‐cause mortality · children with bronchiectasis
1 finding from 1 review
Quality of life not reported · children with bronchiectasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Exacerbations ‐ not reported · children with bronchiectasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Hospitalisation ‐ not reported · children with bronchiectasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Hospitalisation (any cause) · adults with bronchiectasis
Macrolides showed no clear difference in hospitalisation: all cause compared with placebo (low certainty).
1 finding from 1 review
Serious adverse events ‐ not reported · children with bronchiectasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · children with bronchiectasis
1 finding from 1 review
Quality of life ‐ not reported · children with bronchiectasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse events · adults with bronchiectasis
Macrolides showed no clear difference in serious adverse events compared with placebo (low certainty).
1 finding from 1 review