What do systematic reviews say?

Hyperbaric oxygen vs No HBO therapy

Hyperbaric oxygen (HBO) therapy showed no clear difference in postimplantation complications compared with no HBO therapy; GRADE not reported.

• Interventions for replacing missing teeth: hyperbaric oxygen therapy for irradiated patients who require dental implants 2013 · Cochrane All outcomes

  1 year after delivery of the prosthesis
  RR 5.0 [0.27, 94.34]
  1 study · 24 participants
  GRADE not reported

Pre-radiotherapy dental extraction vs Post-radiotherapy dental extraction

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Combined HBO and perioperative antibiotics prior to dental implant therapy vs antibiotics alone

• Interventions for preventing osteoradionecrosis of the jaws in adults receiving head and neck radiotherapy 2019 · Cochrane All outcomes

  1 year
  This comparison was only made in 1 study which reported no serious adverse events associated with HBO therapy. Quality of life measures (oral status, functioning, satisfaction) showed emotional functioning and pain…
  1 study · 26 participants
  Very low

Combined HBO and perioperative antibiotics prior to dental implant therapy vs antibiotics alone

It is very uncertain whether combined HBO and perioperative antibiotics prior to dental implant… changes incidence of ORN compared with antibiotics alone prior to dental implant therapy (very low certainty).

• Interventions for preventing osteoradionecrosis of the jaws in adults receiving head and neck radiotherapy 2019 · Cochrane All outcomes

  1 year
  RR 3.00 [0.14, 65.16]
  1 study · 26 participants
  Very low

Radiotherapy (morning) vs Radiotherapy (afternoon/evening)

Radiotherapy (morning) showed no clear difference in oral mucositis (moderate to severe) compared with radiotherapy (afternoon/evening); GRADE not reported.

• Interventions for preventing oral mucositis for patients with cancer receiving treatment 2011 · Cochrane All outcomes

  Median 28 days
  RR 0.7 [0.48, 1.01]
  1 study · 177 participants
  GRADE not reported

Radiotherapy (morning) vs Radiotherapy (afternoon/evening)

• Interventions for preventing oral mucositis for patients with cancer receiving treatment 2011 · Cochrane All outcomes

  Median 28 days
  no estimate extracted
  2 studies
  GRADE not reported

Endodontic therapy performed with one type of magnification device (surgical microscope, endoscope or magnifying loupes) vs Endodontic therapy performed with a different type of magnification device

The review found no eligible studies for this question.

• Magnification devices for endodontic therapy 2015 · Cochrane All outcomes
  No included study assessed this outcome; the review notes that such secondary outcomes were only sporadically reported and were never statistically assessed.
  Studies not reported
  No studies found

Endodontic therapy performed with one type of magnification device (surgical microscope, endoscope or magnifying loupes) vs Endodontic therapy performed with a different type of magnification device

The review found no eligible studies for this question.

• Magnification devices for endodontic therapy 2015 · Cochrane All outcomes
  No included study assessed this outcome; the review notes that such secondary outcomes were only sporadically reported and were never statistically assessed.
  Studies not reported
  No studies found

Endodontic therapy performed with one type of magnification device (surgical microscope, endoscope or magnifying loupes) vs Endodontic therapy performed with a different type of magnification device

The review found no eligible studies for this question.

• Magnification devices for endodontic therapy 2015 · Cochrane All outcomes
  No included study assessed procedure time. In the excluded trial Taschieri 2008, based on the operators' experience, completing the surgical procedure took on average four to five minutes longer for the endoscope than…
  Studies not reported
  No studies found

Endodontic therapy performed with one type of magnification device (surgical microscope, endoscope or magnifying loupes) vs Endodontic therapy performed with a different type of magnification device

The review found no eligible studies for this question.

• Magnification devices for endodontic therapy 2015 · Cochrane All outcomes

  >=1 year after treatment
  None of the studies fulfilled our inclusion criteria; the only trial comparing three magnification devices (Taschieri 2008) was excluded, so no data analysis was conducted.
  Studies not reported
  No studies found

Endodontic therapy performed with one type of magnification device (surgical microscope, endoscope or magnifying loupes) vs Endodontic therapy performed with a different type of magnification device

The review found no eligible studies for this question.

• Magnification devices for endodontic therapy 2015 · Cochrane All outcomes
  No included study assessed this outcome; the review notes that such secondary outcomes were only sporadically reported and were never statistically assessed.
  Studies not reported
  No studies found

Endodontic therapy performed with one type of magnification device (surgical microscope, endoscope or magnifying loupes) vs Endodontic therapy performed with a different type of magnification device

The review found no eligible studies for this question.

• Magnification devices for endodontic therapy 2015 · Cochrane All outcomes
  No included study assessed this outcome; the review notes that such secondary outcomes were only sporadically reported and were never statistically assessed.
  Studies not reported
  No studies found