Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

121 questions · 139 findings · 14 reviews · Effective Practice and Organisation of Care

No studies found 19 · 13.7%GRADE not reported 10 · 7.2%Very low 56 · 40.3%Low 40 · 28.8%Moderate 11 · 7.9%High 3 · 2.2%

Primary objective: mobile stock notification with effective product transport vs usual care

Proportion of healthcare workers who reported a stockout of drugs in the last 30 days (stockout of artemether‐lumefantrine 2 X 6 to treat malaria caused by Plasmodium facilparum) · healthcare workers and other health professionals involved in commodity and stock management

It is very uncertain whether primary objective: mobile stock notification with effective product… changes proportion of healthcare workers who reported a stockout of drugs in… compared with standard care (very low certainty).

1 finding from 1 review

Primary objective: mobile stock notification with enhanced management vs usual care

Proportion of healthcare workers who reported a stockout of drugs in the last 30 days (stockout of artemether‐lumefantrine 2 X 6 to treat malaria caused by Plasmodium facilparum) · healthcare workers and other health professionals involved in commodity and stock management

It is very uncertain whether primary objective: mobile stock notification with enhanced management changes proportion of healthcare workers who reported a stockout of drugs in… compared with standard care (very low certainty).

1 finding from 1 review

Intervention not reported

Finding 13. Healthcare providers and policymakers highlighted the need for adequate equipment, infrastructure and maintenance both on the provider side and the patient side but described how these needs were not always met. They described challeng...
1 finding from 1 review

Intervention not reported

Anthropometric recovery: percentage of children who recover from moderate or severe wasting Defined as % children aged 6–59 months who recovered in treatment programmes for moderate or severe malnutrition (Wroe 2021) · children aged > 6 months and ≤ 5 years with wasting
1 finding from 1 review

Intervention not reported

Anthropometric recovery: improvement from severe wasting Defined as MUAC ≥ 115 mm, clinically well, absence of oedema for 2 consecutive visits, and minimum stay of 8 weeks in the programme (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention may leads to lower anthropometric recovery: improvement from severe wasting Defined as… (low certainty).

1 finding from 1 review

Intervention not reported

Anthropometric recovery Defined as: WHZ ≥ −1.5 or MUAC > 125 mm for 2 consecutive visits and absence of nutritional oedema for 14 days (Alvarez Moran 2018b); absence of oedema and WHZ ≥ −1.5 or MUAC > 125 mm (Charle‐Cuellar 2021c; no oedema and we... · children aged > 6 months and < 5 years with wasting

It is very uncertain whether the intervention changes anthropometric recovery Defined as: WHZ ≥ −1.5 or MUAC > 125 mm for… (very low certainty).

1 finding from 1 review

Intervention not reported

Anthropometric outcomes: MUAC gain per day Defined as (discharge MUAC − admission MUAC)/days in treatment among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting
1 finding from 1 review

Intervention not reported

Anthropometric outcomes: total weight gain (g/kg) Defined as (weight at discharge − weight on admission)/weight on admission among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting
1 finding from 1 review

Intervention not reported

Anthropometric outcomes: median weight gain per day (g/kg/d) Defined as ((discharge weight − admission weight)/weight on admission)/days on treatment among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting
1 finding from 1 review

Intervention not reported

Anthropometric outcomes: number of children with normal or underweight WHZ on discharge Defined as WHZ > −2 (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with normal or… (low certainty).

1 finding from 1 review

Intervention not reported

Anthropometric outcomes: number of children with WHZ in moderate wasting range on discharge Defined as WHZ between −3 and −2 (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with WHZ in moderate… (moderate certainty).

1 finding from 1 review

Intervention not reported

Anthropometric outcomes: number of children with WHZ in severe wasting range on discharge Defined as WHZ < −3: Hussain 2021 · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with WHZ in severe… (moderate certainty).

1 finding from 1 review

Intervention not reported

Anthropometric outcomes: number of children with MUAC ≥ 115 mm on discharge (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with MUAC ≥ 115 mm on… (moderate certainty).

1 finding from 1 review

Intervention not reported

Anthropometric outcomes: weight gain per day (g/kg/day) Calculated as ((discharge weight − admission weight)/weight on admission)/days in treatment among recovered children (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting
1 finding from 1 review

Lay health worker‐led interventions for adult patients with harmful or hazardous alcohol or substance use vs enhanced usual care

Prevalence of methamphetamine use (1 to 6 months post intervention) (RR < 1 denotes lower prevalence compared to control) · adult patients with harmful or hazardous alcohol or substance use

Lay health worker‐led interventions for adult patients with harmful… showed no clear difference in prevalence of methamphetamine use (1 to 6 months post intervention)… compared with enhanced usual care (low certainty).

1 finding from 1 review