Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

136 questions · 140 findings · 17 reviews · Vascular

No studies found 22 · 15.7%GRADE not reported 13 · 9.3%Very low 28 · 20%Low 50 · 35.7%Moderate 18 · 12.9%High 9 · 6.4%

Phlebotonics vs placebo?

Oedema in the lower legs (dichotomous variable) · patients with venous insufficiency

Do phlebotonics improve signs and symptoms of venous insufficiency… probably leads to lower oedema in the lower legs (dichotomous variable) compared with placebo? (moderate certainty).

1 finding from 1 review

Retrievable vena caval filters with anticoagulation vs anticoagulation

Symtomatic lower extremity venous thrombosis confirmed by Doppler ultrasound or venography (up to 6 months) · participants with unprovoked acute symptomatic PE and at high risk for recurrent PEa

Retrievable vena caval filters with anticoagulation showed no clear difference in symtomatic lower extremity venous thrombosis confirmed by Doppler… compared with anticoagulation (moderate certainty).

1 finding from 1 review

Hand‐assisted laparoscopic repair vs EVAR

Major complications ‐ lower limb ischaemia (up to 12 months) · People undergoing elective abdominal aortic aneurysm repair

Hand‐assisted laparoscopic repair showed no clear difference in major complications ‐ lower limb ischaemia (up to 12 months) compared with EVAR (low certainty).

1 finding from 1 review

Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)

Limb salvage · people who underwent a lower limb revascularisation

Duplex ultrasound plus pulse palpation and arterial pressure index… showed no clear difference in limb salvage rate compared with pulse palpation plus arterial pressure index (ABI or TBI) (short term) (low certainty).

1 finding from 1 review

Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)

Secondary patency (24 months) · people who underwent a lower limb revascularisation

Duplex ultrasound plus pulse palpation and arterial pressure index… showed no clear difference in vessel or graft secondary patency compared with pulse palpation plus arterial pressure index (ABI or TBI) (short term) (low certainty).

1 finding from 1 review

Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)

All‐cause mortality · people who underwent a lower limb revascularisation

Duplex ultrasound plus pulse palpation and arterial pressure index… showed no clear difference in all‐cause mortality compared with pulse palpation plus arterial pressure index (ABI or TBI) (short term) (low certainty).

1 finding from 1 review