Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

558 questions · 586 findings · 46 reviews · Pregnancy and Childbirth

No studies found 151 · 25.8%GRADE not reported 53 · 9%Very low 124 · 21.2%Low 157 · 26.8%Moderate 76 · 13%High 25 · 4.3%

Interventionist care vs expectant care

Intraventricular haemorrhage or hypoxic ischaemic encephalopathy · women with severe pre‐eclampsia between 24 and 34 weeks' gestation

Interventionist care probably leads to higher intraventricular haemorrhage or hypoxic ischaemic encephalopathy compared with expectant (delayed delivery) care (moderate certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Abstinence · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy leads to higher abstinence at 0 to 5 months postpartum compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

2 findings from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Birthweight < 2500 (g) · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy leads to lower low birthweight (under 2500 g) compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Gestational age (preterm birth < 37 weeks) · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy showed no clear difference in preterm birth (under 37 weeks) compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Mean birthweight · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy showed no clear difference in mean birthweight (g) compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Stillbirth · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy showed no clear difference in stillbirths compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Admission to NICU (primary outcome)№ of participants: 204(1 RCT) · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy leads to lower NICU admissions compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Lifestyle interventions vs control ‐ Maternal outcomes

Hypertensive disorders of pregnancy: pre‐eclampsia · women with gestational diabetes mellitus

Lifestyle interventions showed no clear difference in hypertensive disorders of pregnancy (pre‐eclampsia) compared with control ‐ Maternal outcomes (low certainty).

1 finding from 1 review

Lifestyle interventions vs control ‐ Maternal outcomes

Postnatal weight retention or return to pre‐pregnancy weight · women with gestational diabetes mellitus

Lifestyle interventions may leads to higher postnatal weight retention or return to pre‐pregnancy weight compared with control ‐ Maternal outcomes (low certainty).

1 finding from 1 review