Findings

What do systematic reviews say?

94 questions · 102 findings · 12 reviews · Vascular

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No studies found 16 · 15.7%GRADE not reported 1 · 1%Very low 17 · 16.7%Low 32 · 31.4%Moderate 27 · 26.5%High 9 · 8.8%

Cilostazol vs pentoxifylline

Change in claudication distance from baseline (m) · intermittent claudication

1 finding from 1 review

Cilostazol for intermittent claudication 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 417 participants
Low

Cilostazol vs pentoxifylline

Quality of life (change in points, SF‐36, WIQ) · intermittent claudication

1 finding from 1 review

Cilostazol for intermittent claudication 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 317 participants
Very low

Propionyl‐L‐carnitine vs placebo

Absolute claudication distance (MWD + PWT) (in meters) · intermittent claudication

1 finding from 1 review

Propionyl‐L‐carnitine for intermittent claudication 2021 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1121 participants
Moderate

Propionyl‐L‐carnitine vs L‐carnitine

Progression of disease (to Fontaine stage III or IV or necessity for intervention (endovascular or surgery)) · intermittent claudication

The review found no eligible studies for this question.

1 finding from 1 review

Propionyl‐L‐carnitine for intermittent claudication 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Propionyl‐L‐carnitine vs L‐carnitine

Side effects of propionyl‐L‐carnitine regimen · intermittent claudication

The review found no eligible studies for this question.

1 finding from 1 review

Propionyl‐L‐carnitine for intermittent claudication 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Propionyl‐L‐carnitine vs L‐carnitine

Ankle brachial index · intermittent claudication

The review found no eligible studies for this question.

1 finding from 1 review

Propionyl‐L‐carnitine for intermittent claudication 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Propionyl‐L‐carnitine vs placebo

Initial claudication distance (PFWD + COT) (in meters) · intermittent claudication

1 finding from 1 review

Propionyl‐L‐carnitine for intermittent claudication 2021 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1151 participants
Moderate

Propionyl‐L‐carnitine vs placebo

Quality of life · intermittent claudication

1 finding from 1 review

Propionyl‐L‐carnitine for intermittent claudication 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 126 participants
Moderate

Propionyl‐L‐carnitine vs placebo

Progression of disease (to Fontaine stage III or IV, or necessity for intervention (endovascular or surgery)) · intermittent claudication

1 finding from 1 review

Propionyl‐L‐carnitine for intermittent claudication 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 485 participants
Low

Propionyl‐L‐carnitine vs placebo

Side effects of propionyl‐L‐carnitine regimen · intermittent claudication

1 finding from 1 review

Propionyl‐L‐carnitine for intermittent claudication 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1303 participants
Moderate

Propionyl‐L‐carnitine vs placebo

Ankle brachial index · intermittent claudication

1 finding from 1 review

Propionyl‐L‐carnitine for intermittent claudication 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 369 participants
Moderate

Propionyl‐L‐carnitine vs L‐carnitine

Absolute claudication distance (in meters) · intermittent claudication

1 finding from 1 review

Propionyl‐L‐carnitine for intermittent claudication 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Low

Propionyl‐L‐carnitine vs L‐carnitine

Initial claudication distance (in meters) · intermittent claudication

1 finding from 1 review

Propionyl‐L‐carnitine for intermittent claudication 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Low

Propionyl‐L‐carnitine vs L‐carnitine

Quality of life · intermittent claudication

The review found no eligible studies for this question.

1 finding from 1 review

Propionyl‐L‐carnitine for intermittent claudication 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pentoxifylline vs placebo

PFWD (change in metres) (4–40 weeks' · intermittent claudication

1 finding from 1 review

Pentoxifylline for intermittent claudication 2020 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 1890 participants
Low

Pentoxifylline vs placebo

TWD (change in metres) (8–52 weeks' · intermittent claudication

1 finding from 1 review

Pentoxifylline for intermittent claudication 2020 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 2110 participants
Low

Pentoxifylline vs placebo

ABI (pre‐exercise/baseline ABI compared with · intermittent claudication

1 finding from 1 review

Pentoxifylline for intermittent claudication 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 902 participants
Moderate

Pentoxifylline vs placebo

QoL · intermittent claudication

1 finding from 1 review

Pentoxifylline for intermittent claudication 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1179 participants
Moderate

Pentoxifylline vs placebo

Side effects (number of cases or proportion) (4–52 weeks' · intermittent claudication

1 finding from 1 review

Pentoxifylline for intermittent claudication 2020 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1837 participants
Low

Supervised exercise therapy vs home exercises

Maximal treadmill walking distance after 3 months · intermittent claudication

1 finding from 1 review

Supervised exercise therapy versus home‐based exercise therapy versus walking advice for intermittent claudication 2018 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 351 participants
Moderate