Findings

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49 questions · 49 findings · 5 reviews · Infectious Diseases

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No studies found 4 · 8.2%GRADE not reported 0 · 0%Very low 11 · 22.4%Low 8 · 16.3%Moderate 23 · 46.9%High 3 · 6.1%

Intervention not reported

Parasitaemia · malaria in infants

The review found no eligible studies for this question.

1 finding from 1 review

Intermittent preventive treatment for malaria in infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Anaemia · malaria in infants

The intervention showed no clear difference in anaemia (moderate certainty).

1 finding from 1 review

Intermittent preventive treatment for malaria in infants 2021 · Cochrane Headline outcomes only
Rate ratio 0.72 [0.49, 1.07]
1 study · 676 participants
Moderate

Intervention not reported

All‐cause mortality · children under 12 months of age

The intervention showed no clear difference in all‐cause mortality (moderate certainty).

1 finding from 1 review

Intermittent preventive treatment for malaria in infants 2021 · Cochrane Headline outcomes only
Risk ratio 0.93 [0.74, 1.15]
9 studies · 14588 participants
Moderate

Intervention not reported

Hospital admission for any reason · children under 12 months of age

The intervention probably leads to lower hospital admission for any reason (moderate certainty).

1 finding from 1 review

Intermittent preventive treatment for malaria in infants 2021 · Cochrane Headline outcomes only
Rate ratio 0.85 [0.78, 0.93]
7 studies · 7486 participants
Moderate

Intervention not reported

Parasitaemia · children under 12 months of age

The intervention probably leads to lower parasitaemia (moderate certainty).

1 finding from 1 review

Intermittent preventive treatment for malaria in infants 2021 · Cochrane Headline outcomes only
Rate ratio 0.66 [0.56, 0.79]
1 study · 1200 participants
Moderate

Intervention not reported

Anaemia · children under 12 months of age

The intervention probably leads to lower anaemia (moderate certainty).

1 finding from 1 review

Intermittent preventive treatment for malaria in infants 2021 · Cochrane Headline outcomes only
Rate ratio 0.82 [0.68, 0.98]
6 studies · 7438 participants
Moderate

Intervention not reported

Clinical malaria · malaria in infants

The intervention probably leads to lower clinical malaria (moderate certainty).

1 finding from 1 review

Intermittent preventive treatment for malaria in infants 2021 · Cochrane Headline outcomes only
Rate ratio 0.75 [0.61, 0.94]
1 study · 547 participants
Moderate

Intervention not reported

Severe malaria · malaria in infants

The review found no eligible studies for this question.

1 finding from 1 review

Intermittent preventive treatment for malaria in infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

All‐cause mortality · malaria in infants

The intervention showed no clear difference in all‐cause mortality (moderate certainty).

1 finding from 1 review

Intermittent preventive treatment for malaria in infants 2021 · Cochrane Headline outcomes only
Risk ratio 1.21 [0.58, 2.55]
1 study · 684 participants
Moderate

Intervention not reported

Death or hospital admission · Children with anaemia

The intervention showed no clear difference in death or hospital admission (moderate certainty).

1 finding from 1 review

Intermittent preventive antimalarial treatment for children with anaemia 2015 · Cochrane Headline outcomes only
RR 0.9 [0.71, 1.13]
3 studies · 3160 participants
Moderate

Intervention not reported

Children with anaemia (Hb < 11 g/dL) · Children with anaemia

The intervention showed no clear difference in children with anaemia (Hb < 11 g/dL) (moderate certainty).

1 finding from 1 review

Intermittent preventive antimalarial treatment for children with anaemia 2015 · Cochrane Headline outcomes only
RR 0.97 [0.88, 1.07]
4 studies · 2237 participants
Moderate

Intervention not reported

Mean change in Hb from baseline · Children with anaemia

1 finding from 1 review

Intermittent preventive antimalarial treatment for children with anaemia 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1672 participants
Moderate

Intervention not reported

Mean Hb · Children with anaemia

1 finding from 1 review

Intermittent preventive antimalarial treatment for children with anaemia 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1672 participants
Low

Intervention not reported

Clinical malaria · Children aged less than 5 years

The intervention leads to lower clinical malaria (high certainty).

1 finding from 1 review

Intermittent preventive treatment for malaria in children living in areas with seasonal transmission 2012 · Cochrane Headline outcomes only
Rate Ratio 0.26 [0.17, 0.38]
6 studies · 9321 participants
High

Intervention not reported

Severe malaria · Children aged less than 5 years

The intervention leads to lower severe malaria (high certainty).

1 finding from 1 review

Intermittent preventive treatment for malaria in children living in areas with seasonal transmission 2012 · Cochrane Headline outcomes only
Rate Ratio 0.27 [0.1, 0.76]
2 studies · 5964 participants
High

Intervention not reported

Death from any cause · Children aged less than 5 years

The intervention showed no clear difference in death from any cause (moderate certainty).

1 finding from 1 review

Intermittent preventive treatment for malaria in children living in areas with seasonal transmission 2012 · Cochrane Headline outcomes only
Risk Ratio 0.66 [0.31, 1.39]
6 studies · 9533 participants
Moderate

Intervention not reported

Moderately severe anaemia · Children aged less than 5 years

The intervention probably leads to lower moderately severe anaemia (moderate certainty).

1 finding from 1 review

Intermittent preventive treatment for malaria in children living in areas with seasonal transmission 2012 · Cochrane Headline outcomes only
Risk Ratio 0.71 [0.52, 0.98]
5 studies · 8805 participants
Moderate

Intervention not reported

Serious drug related adverse events · Children aged less than 5 years

1 finding from 1 review

Intermittent preventive treatment for malaria in children living in areas with seasonal transmission 2012 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 9533 participants
Moderate

Intervention not reported

Non‐serious adverse events · Children aged less than 5 years

1 finding from 1 review

Intermittent preventive treatment for malaria in children living in areas with seasonal transmission 2012 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 9533 participants
Moderate

Intervention not reported

Maternal parasitaemia (at delivery) · HIV‐positive pregnant women living

The intervention may leads to lower maternal parasitaemia (at delivery) (low certainty).

1 finding from 1 review

Intermittent preventive treatment regimens for malaria in HIV‐positive pregnant women 2011 · Cochrane Headline outcomes only
RR 0.25 [0.14, 0.43]
2 studies · 463 participants
Low