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Evidence found and GRADE certainty

28 questions · 29 findings · 5 reviews · Neuromuscular

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No studies found 7 · 24.1%GRADE not reported 1 · 3.4%Very low 5 · 17.2%Low 6 · 20.7%Moderate 8 · 27.6%High 2 · 6.9%

IVIg vs PE

Relapse or treatment‐related fluctuation · patients with Guillain‐Barré syndrome

IVIg showed no clear difference in relapse or treatment‐related fluctuation compared with PE (low certainty).

1 finding from 1 review

IVIg vs PE

Patients in whom treatment was discontinued · patients with Guillain‐Barré syndrome

IVIg leads to lower participants in whom treatment was discontinued compared with PE (high certainty).

1 finding from 1 review

IVIg vs PE

Number of patients with adverse events attributed to treatment · patients with Guillain‐Barré syndrome

IVIg showed no clear difference in number of participants with adverse events attributed to treatment compared with PE (moderate certainty).

1 finding from 1 review

Methotrexate vs placebo

Participants able to reduce corticosteroid or IVIg dose by more than 20% · people with CIDP

Methotrexate showed no clear difference in participants able to reduce corticosteroid or IVIg dose by more than… compared with placebo (moderate certainty).

1 finding from 1 review

Interferon beta‐1a vs placebo

Participants who completed the study and did not restart IVIg therapy after IVIg withdrawal · people with CIDP

Interferon beta‐1a showed no clear difference in participants who completed the study and did not restart IVIg… compared with placebo (moderate certainty).

1 finding from 1 review