Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

114 questions · 127 findings · 8 reviews

No studies found 13 · 10.2%GRADE not reported 0 · 0%Very low 35 · 27.6%Low 70 · 55.1%Moderate 9 · 7.1%High 0 · 0%

Intervention not reported

Live birth or ongoing pregnancy: prior cycle vs IUI cycle · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Clinical pregnancy: prior cycle vs IUI cycle (sensitivity analysis) · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

It is very uncertain whether the intervention changes clinical pregnancy: prior cycle vs IUI cycle (sensitivity analysis) (very low certainty).

1 finding from 1 review

IUI in a natural cycle vs TI or expectant management

Multiple pregnancy rate · participants with unexplained subfertility

IUI in a natural cycle showed no clear difference in multiple pregnancy rate per couple compared with TI or expectant management (low certainty).

2 findings from 1 review

IUI in a natural cycle vs TI or expectant management

Pregnancy rate per couple (all cycles) · participants with unexplained subfertility

IUI in a natural cycle probably leads to higher pregnancy rate per couple (all cycles) compared with TI or expectant management (moderate certainty).

2 findings from 1 review

IUI in a natural cycle vs TI or expectant management

Ovarian Hyperstimulation Syndrome rate per woman ‐ not reported · participants with unexplained subfertility

The review found no eligible studies for this question.

2 findings from 1 review

IUI in a natural cycle vs TI or expectant management

Ectopic pregnancy rate per couple · participants with unexplained subfertility

IUI in a natural cycle showed no clear difference in ectopic pregnancy rate per couple compared with TI or expectant management (low certainty).

2 findings from 1 review

IUI in a stimulated cycle vs TI

Pregnancy rate per couple (all cycles) · couples with male subfertility

It is very uncertain whether IUI in stimulated cycles changes pregnancy rate per couple (all cycles) compared with TI (very low certainty).

2 findings from 1 review

IUI in a stimulated cycle vs TI

Live birth rate per couple · couples with male subfertility

IUI in stimulated cycles showed no clear difference in live birth rate per couple (all cycles) compared with TI (low certainty).

2 findings from 1 review