Findings

What do systematic reviews say?

172 questions · 179 findings · 40 reviews · Musculoskeletal

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No studies found 21 · 11.7%GRADE not reported 7 · 3.9%Very low 24 · 13.4%Low 68 · 38%Moderate 45 · 25.1%High 14 · 7.8%

High‐dose colchicine vs placebo

Pain ‐ not reported · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

High‐dose colchicine vs placebo

Participant global assessment of treatment success: proportion with 50% or greater decrease in pain score from baseline ‐ 32 to 36 hours · acute gout

High‐dose colchicine may leads to higher participant global assessment of treatment success: proportion with… compared with placebo (low certainty).

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
RR 2.16 [1.28, 3.65]
2 studies · 124 participants
Low

Closing wedge high tibial osteotomy (CW‐HTO) vs unicompartmental knee arthroplasty

Function · patients with osteoarthritis of the knee

The review found no eligible studies for this question.

1 finding from 1 review

Osteotomy for treating knee osteoarthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Closing wedge high tibial osteotomy (CW‐HTO) vs unicompartmental knee arthroplasty

Health‐related quality of life measures Participant opinion: improvement · patients with osteoarthritis of the knee

The review found no eligible studies for this question.

1 finding from 1 review

Osteotomy for treating knee osteoarthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Closing wedge high tibial osteotomy (CW‐HTO) vs unicompartmental knee arthroplasty

Adverse events · patients with osteoarthritis of the knee

It is very uncertain whether closing wedge high tibial osteotomy (CW‐HTO) changes adverse events compared with unicompartmental knee arthroplasty (very low certainty).

1 finding from 1 review

Osteotomy for treating knee osteoarthritis 2014 · Cochrane Headline outcomes only
RR 0.25 [0.06, 1.08]
1 study · 60 participants
Very low

Closing wedge high tibial osteotomy (CW‐HTO) vs unicompartmental knee arthroplasty

All‐cause mortality · patients with osteoarthritis of the knee

The review found no eligible studies for this question.

1 finding from 1 review

Osteotomy for treating knee osteoarthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Closing wedge high tibial osteotomy (CW‐HTO) vs unicompartmental knee arthroplasty

Reoperation rate · patients with osteoarthritis of the knee

The review found no eligible studies for this question.

1 finding from 1 review

Osteotomy for treating knee osteoarthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Closing wedge high tibial osteotomy (CW‐HTO) vs unicompartmental knee arthroplasty

Treatment failure rate · patients with osteoarthritis of the knee

It is very uncertain whether closing wedge high tibial osteotomy (CW‐HTO) changes treatment failure rate compared with unicompartmental knee arthroplasty (very low certainty).

1 finding from 1 review

Osteotomy for treating knee osteoarthritis 2014 · Cochrane Headline outcomes only
RR 1.32 [0.94, 1.87]
1 study · 60 participants
Very low

Closing wedge high tibial osteotomy (CW‐HTO) vs unicompartmental knee arthroplasty

Pain · patients with osteoarthritis of the knee

The review found no eligible studies for this question.

1 finding from 1 review

Osteotomy for treating knee osteoarthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any cold therapy vs no cold therapy following total knee replacement

Blood lossTime point: mean 48 hours, range 1 to 13 days. Higher blood loss indicates a worse outcome. · people undergoing total knee replacement

1 finding from 1 review

Cryotherapy following total knee replacement 2023 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 956 participants
Low

Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care

Physical function · systemic lupus erythematosus

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 182 participants
Low

Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo + standard care

Functional capacity · systemic lupus erythematosus

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Low

Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone

Physical function · systemic lupus erythematosus

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 96 participants
Low

Custom foot orthoses vs shoes

QoL · children with juvenile idiopathic arthritis and flat feet

2 findings from 1 review

Foot orthoses for treating paediatric flat feet 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low
Foot orthoses for treating paediatric flat feet 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Prefabricated foot orthoses vs shoes

QoL · children with juvenile idiopathic arthritis and flat feet

2 findings from 1 review

Foot orthoses for treating paediatric flat feet 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low
Foot orthoses for treating paediatric flat feet 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Custom foot orthoses vs prefabricated foot orthoses

QoL · children with juvenile idiopathic arthritis and flat feet

2 findings from 1 review

Foot orthoses for treating paediatric flat feet 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low
Foot orthoses for treating paediatric flat feet 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Prefabricated foot orthoses vs shoes

QoL · children with symptomatic flat feet

1 finding from 1 review

Foot orthoses for treating paediatric flat feet 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Mobility training vs control

Mobility · older people living in the community with frailty

1 finding from 1 review

Mobility training for increasing mobility and functioning in older people with frailty 2022 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 1151 participants
High

Mobility training vs control: subgroups with or without cognitive impairments

Level of functioning · older people living in the community with frailty

2 findings from 1 review

Mobility training for increasing mobility and functioning in older people with frailty 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 80 participants
Very low
Mobility training for increasing mobility and functioning in older people with frailty 2022 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 839 participants
Moderate

Mobility training vs control: subgroups with or without cognitive impairments

Mobility · older people living in the community with frailty

2 findings from 1 review

Mobility training for increasing mobility and functioning in older people with frailty 2022 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 967 participants
High
Mobility training for increasing mobility and functioning in older people with frailty 2022 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 171 participants
Low