What do systematic reviews say?

Rabeprazole at higher doses (1 mg/kg) vs rabeprazole at lower doses (0.5 mg/kg)

The review found no eligible studies for this question.

• Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pantoprazole in higher doses (1.2 mg/kg) vs pantoprazole at lower doses (0.3 mg/kg)

• Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Very low

Pantoprazole in higher doses (1.2 mg/kg) vs pantoprazole at lower doses (0.3 mg/kg)

• Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Very low

Pantoprazole in higher doses (1.2 mg/kg) vs pantoprazole at lower doses (0.3 mg/kg)

The review found no eligible studies for this question.

• Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pantoprazole in higher doses (1.2 mg/kg) vs pantoprazole at lower doses (0.3 mg/kg)

The review found no eligible studies for this question.

• Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Higher threshold (500 mL per six hours or greater) vs lower threshold (less than 500 mL per six hours) at time of aspiration

It is very uncertain whether higher threshold (500 mL per six hours or greater) changes mortality (at the end of compared with lower threshold (less than 500 mL per six hours) at time of aspiration (very low certainty).

• Monitoring of gastric residual volume during enteral nutrition 2021 · Cochrane Headline outcomes only
  RR 1.01 [0.74, 1.38]
  1 study · 322 participants
  Very low

Higher threshold (500 mL per six hours or greater) vs lower threshold (less than 500 mL per six hours) at time of aspiration

It is very uncertain whether higher threshold (500 mL per six hours or greater) changes pneumonia (until discontinued or up to 28 days) compared with lower threshold (less than 500 mL per six hours) at time of aspiration (very low certainty).

• Monitoring of gastric residual volume during enteral nutrition 2021 · Cochrane Headline outcomes only
  RR 1.03 [0.72, 1.46]
  1 study · 322 participants
  Very low

Higher threshold (500 mL per six hours or greater) vs lower threshold (less than 500 mL per six hours) at time of aspiration

• Monitoring of gastric residual volume during enteral nutrition 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 322 participants
  Very low

High‐treatment‐dose vitamin D (greater than 1000 IU/day) vs low‐treatment‐dose vitamin D (400 IU/day to 1000 IU/day)

The review found no eligible studies for this question.

• Vitamin D for the treatment of inflammatory bowel disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

High‐treatment‐dose vitamin D (greater than 1000 IU/day) vs low‐treatment‐dose vitamin D (400 IU/day to 1000 IU/day)

High‐treatment‐dose vitamin D (greater than 1000 IU/day) showed no clear difference in clinical relapse at end of study (52 weeks) compared with low‐treatment‐dose vitamin D (400 IU/day to 1000 IU/day) (low certainty).

• Vitamin D for the treatment of inflammatory bowel disease 2023 · Cochrane Headline outcomes only
  RR 0.48 [0.23, 1.01]
  1 study · 34 participants
  Low

High‐treatment‐dose vitamin D (greater than 1000 IU/day) vs low‐treatment‐dose vitamin D (400 IU/day to 1000 IU/day)

• Vitamin D for the treatment of inflammatory bowel disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 46 participants
  Very low

High‐treatment‐dose vitamin D (greater than 1000 IU/day) vs low‐treatment‐dose vitamin D (400 IU/day to 1000 IU/day)

It is very uncertain whether high‐treatment‐dose vitamin D (greater than 1000 IU/day) changes withdrawals due to adverse events compared with low‐treatment‐dose vitamin D (400 IU/day to 1000 IU/day) (very low certainty).

• Vitamin D for the treatment of inflammatory bowel disease 2023 · Cochrane Headline outcomes only
  RR 0.89 [0.06, 13.08]
  3 studies · 104 participants
  Very low

High‐volume continuous veno‐venous hemofiltration (CVVH) vs standard CVVH

The review found no eligible studies for this question.

• Continuous veno‐venous hemofiltration for severe acute pancreatitis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

High‐volume continuous veno‐venous hemofiltration (CVVH) vs standard CVVH

The review found no eligible studies for this question.

• Continuous veno‐venous hemofiltration for severe acute pancreatitis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

High‐volume continuous veno‐venous hemofiltration (CVVH) vs standard CVVH

The review found no eligible studies for this question.

• Continuous veno‐venous hemofiltration for severe acute pancreatitis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

High‐volume continuous veno‐venous hemofiltration (CVVH) vs standard CVVH

High‐volume continuous veno‐venous hemofiltration (CVVH) showed no clear difference in all‐cause mortality compared with standard CVVH (low certainty).

• Continuous veno‐venous hemofiltration for severe acute pancreatitis 2019 · Cochrane Headline outcomes only
  RR 0.6 [0.17, 2.07]
  1 study · 30 participants
  Low

High‐volume continuous veno‐venous hemofiltration (CVVH) vs standard CVVH

It is very uncertain whether high‐volume continuous veno‐venous hemofiltration (CVVH) changes adverse events compared with standard CVVH (very low certainty).

• Continuous veno‐venous hemofiltration for severe acute pancreatitis 2019 · Cochrane Headline outcomes only
  RR 1 [0.16, 6.2]
  1 study · 30 participants
  Very low

High‐volume continuous veno‐venous hemofiltration (CVVH) vs standard CVVH

The review found no eligible studies for this question.

• Continuous veno‐venous hemofiltration for severe acute pancreatitis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Weekly educational texts messages vs once every other week educational text messages

• Patient education interventions for the management of inflammatory bowel disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 193 participants
  Very low

Web‐based patient education vs other delivery of patient education

• Patient education interventions for the management of inflammatory bowel disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 58 participants
  Very low