Cochrane · systematic review · CD012959
Continuous veno‐venous hemofiltration for severe acute pancreatitis
Lin, Y, He, S, Gong, J, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
6
No studies
6
Included studies
NR
No studies 6 · 50%Ungraded 0 · 0%Very low 5 · 41.7%Low 1 · 8.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Continuous veno‐venous hemofiltration (CVVH) compared to no CVVH for severe acute pancreatitis
Population: adults with severe acute pancreatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality Continuous veno‐venous hemofiltration (CVVH) vs no CVVH | 0.62 [0.27, 1.4] | 2 studies · 189 participants | Very low Downgraded: risk of bias |
Adverse events Continuous veno‐venous hemofiltration (CVVH) vs no CVVH | no estimate extracted | NR | No studies |
Length of ICU stay Continuous veno‐venous hemofiltration (CVVH) vs no CVVH | no estimate extracted | 1 study · 125 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Length of hospital stay Continuous veno‐venous hemofiltration (CVVH) vs no CVVH | no estimate extracted | 1 study · 125 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Total hospital cost Continuous veno‐venous hemofiltration (CVVH) vs no CVVH | no estimate extracted | 1 study · 125 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Quality of life Continuous veno‐venous hemofiltration (CVVH) vs no CVVH | no estimate extracted | NR | No studies |
High‐volume continuous veno‐venous hemofiltration (CVVH) compared to standard CVVH for severe acute pancreatitis
Population: adults with severe acute pancreatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality High‐volume continuous veno‐venous hemofiltration (CVVH) vs standard CVVH | RR 0.6 [0.17, 2.07] | 1 study · 30 participants | Low Downgraded: risk of bias, imprecision |
Adverse events High‐volume continuous veno‐venous hemofiltration (CVVH) vs standard CVVH | RR 1 [0.16, 6.2] | 1 study · 30 participants | Very low Downgraded: risk of bias, imprecision |
Length of ICU stay High‐volume continuous veno‐venous hemofiltration (CVVH) vs standard CVVH | no estimate extracted | NR | No studies |
Length of hospital stay High‐volume continuous veno‐venous hemofiltration (CVVH) vs standard CVVH | no estimate extracted | NR | No studies |
Total hospital cost High‐volume continuous veno‐venous hemofiltration (CVVH) vs standard CVVH | no estimate extracted | NR | No studies |
Quality of life High‐volume continuous veno‐venous hemofiltration (CVVH) vs standard CVVH | no estimate extracted | NR | No studies |