What do systematic reviews say?

Reduction in physical signs (Severity of impairment) Measured by the VRMC scale (higher is better) · people with conversion disorder according to DSM‐IV or ICD‐10 criteria

Self‐efficacy score Scale: Generalized Self‐Efficacy Scale Direction: higher better · women aged 16 years and older who self‐report previous or current experience of intimate partner violence

Safety planning and/or safety behaviour score Service use and activities questionnaire Direction: higher better · women aged 16 years and older who self‐report previous or current experience of intimate partner violence

QoL · men and women aged over 18 years with chronic fatigue syndrome

Physical quality of life · clinical diagnosis of depression

Quality of life (emotional) · clinical diagnosis of depression

Physical quality of life · clinical diagnosis of depression

Quality of life (emotional) · clinical diagnosis of depression

Relationship distress at the end of treatment Dyadic Adjustment Scale (DAS) or Maudsley Marital Questionnaire (MMQ). DAS is a self‐report inventory with 32 items, with the total score ranging from 0 to 151. Higher scores indicate less distress. MM... · heterosexual adult couples aged > 18 with a partner having a clinical diagnosis of depressive disorder

Relationship distress at the end of treatment Dyadic Adjustment Scale (DAS) or Quality of Marriage Index ‐ QMI. DAS is a self‐report inventory with 32 items, with the total score ranging from 0 to 151. Higher scores indicate less distress. QMI is ... · heterosexual adult couples aged > 18 with a partner having a clinical diagnosis of depressive disorder

Relationship distress at end of treatment Dyadic Adjustment Scale (DAS) or Maudsley Marital Questionnaire (MMQ). DAS is a self‐report inventory with 32 items, with the total score ranging from 0 to 151. Higher scores indicate less distress. MMQ is... · heterosexual adult couples aged > 18 with a partner having a clinical diagnosis of depressive disorder

Relationship distress at post‐treatment Dyadic Adjustment Scale (DAS) or Maudsley Marital Questionnaire (MMQ). DAS is a self‐report inventory with 32 items, with the total score ranging from 0 to 151. Higher scores indicate less distress. MMQ is a... · heterosexual adult couples aged >18 with a partner having a clinical diagnosis of depressive disorder

Next‐day alertness Participant reports. Scale from: 0 to 10 points; higher scores equalled better outcome; CFB and double‐blind average values included · Patients with insomnia

Evidence‐based psychological interventions versus any comparator (Overall) ‐ self‐rated depression scores (higher score is equivalent to a poorer outcome) · Children or adolescents

Evidence‐based psychological interventions versus any comparator (Targeted ‐ self‐rated depression scores (higher score is equivalent to a poorer outcome)) · Children or adolescents

Evidence‐based psychological interventions versus any comparator (Universal programmes) ‐ self‐rated depression scores (higher score is equivalent to a poorer outcome) · Children or adolescents

PTSD severity following treatment completion As assessed by the CAPS, PSS‐I, or IES‐R. High scores indicate greater symptom severity · Individuals with post‐traumatic stress disorder and comorbid substance use disorder

Drug or alcohol use, or both following treatment completion ‐ Group‐based intervention As assessed by the ASI, TLFB or CIDI. High scores indicate greater symptom severity · Individuals with post‐traumatic stress disorder and comorbid substance use disorder

Severity of PTSD symptoms · Individuals with post‐traumatic stress disorder and comorbid substance use disorder

Drug or alcohol use, or both following treatment completion ‐ Individual‐based intervention · Individuals with post‐traumatic stress disorder and comorbid substance use disorder