Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

36 questions · 36 findings · 3 reviews · Gut

No studies found 5 · 13.9%GRADE not reported 1 · 2.8%Very low 2 · 5.6%Low 16 · 44.4%Moderate 10 · 27.8%High 2 · 5.6%

H2 receptor antagonists vs placebo or no prophylaxis

Clinically important upper GI bleeding · people admitted to intensive care units

H2 receptor antagonists probably leads to lower clinically important upper GI bleeding compared with placebo or no prophylaxis (moderate certainty).

1 finding from 1 review