Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

43 questions · 43 findings · 6 reviews · Headline outcomes only

No studies found 3 · 7%GRADE not reported 0 · 0%Very low 18 · 41.9%Low 17 · 39.5%Moderate 2 · 4.7%High 3 · 7%

Fibrin glue instillation under skin flaps vs no‐fibrin

PostoperativecomplicationsRR · people with breast and axillary surgery

Fibrin glue instillation under skin flaps showed no clear difference in postoperativecomplicationsRR compared with no‐fibrin (low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Mortality Total of deaths and the end of · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes mortality Total of deaths and the end of compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Re‐bleeding Bleeding after initial success in the intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes re‐bleeding Bleeding after initial success in the intervention compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Control of bleeding Success in control the active variceal bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes control of bleeding Success in control the active variceal bleeding compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate vs alcohol

Re‐bleeding Re‐bleeding after intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes re‐bleeding Re‐bleeding after intervention compared with alcohol (very low certainty).

1 finding from 1 review

Cyanoacrylate vs alcohol

Control of bleeding Success in control the active variceal bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes control of bleeding Success in controlling the active variceal… compared with alcohol (very low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Failure of intervention Continuous variceal bleeding after intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes failure of intervention Continuous variceal bleeding after… compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Re‐bleeding Re‐bleeding after the bleeding was controlled in the first intervention · acute bleeding gastric varices in people with portal hypertension

Cyanoacrylate may leads to lower re‐bleeding Re‐bleeding after the bleeding was controlled in the… compared with band ligation (low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Complications (general) Number of total complications · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes complications (general) Number of total complications compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Control of bleeding Success in control the active variceal bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes control of bleeding Success in control variceal bleeding compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Total mortality Total deaths and the end of · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes total mortality Total deaths and the end of compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review