Findings

What do systematic reviews say?

28 questions · 28 findings · 1 reviews · Pregnancy and Childbirth

No studies found 16 · 57.1%GRADE not reported 0 · 0%Very low 1 · 3.6%Low 10 · 35.7%Moderate 1 · 3.6%High 0 · 0%

Induction of labour · women with gestational diabetes mellitus

Metformin showed no clear difference in induction of labour compared with glibenclamide ‐ maternal outcomes (low certainty).

1 finding from 1 review

Large‐for‐gestational age · Infants of women diagnosed with gestational diabetes

Metformin showed no clear difference in large‐for‐gestational age compared with glibenclamide ‐ neonatal outcomes (low certainty).

1 finding from 1 review

Perinatal mortality · Infants of women diagnosed with gestational diabetes

It is very uncertain whether metformin changes perinatal mortality compared with glibenclamide ‐ neonatal outcomes (very low certainty).

1 finding from 1 review

Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes 2017 · Cochrane Headline outcomes only
RR 0.92 [0.06, 14.55]
2 studies · 359 participants
Very low

Death or serious morbidity composite · Infants of women diagnosed with gestational diabetes

Metformin may leads to lower death or serious morbidity composite compared with glibenclamide ‐ neonatal outcomes (low certainty).

1 finding from 1 review

Neonatal hypoglycaemia · Infants of women diagnosed with gestational diabetes

Metformin showed no clear difference in neonatal hypoglycaemia compared with glibenclamide ‐ neonatal outcomes (low certainty).

1 finding from 1 review

Adiposity ‐ not reported · Infants of women diagnosed with gestational diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Diabetes ‐ not measured · Infants of women diagnosed with gestational diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Neurosensory disability in later childhood ‐ not measured · Infants of women diagnosed with gestational diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found