What do systematic reviews say?

Summary of findings table ‐ Progestogens vs GnRH antagonists

• Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian hyperstimulation… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1 participants
  GRADE not reported

Blastocyst‐stage vs cleavage‐stage embryo transfer

Blastocyst‐stage may leads to higher live birth rate per fresh transfer compared with cleavage‐stage embryo transfer (low certainty).

• Cleavage‐stage versus blastocyst‐stage embryo transfer in assisted reproductive technology 2022 · Cochrane Headline outcomes only
  OR 1.27 [1.06, 1.51]
  15 studies · 2219 participants
  Low

Swim‐up technique vs gradient technique

The review found no eligible studies for this question.

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Swim‐up technique vs wash and centrifugation

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Very low

Gradient technique vs wash and centrifugation

The review found no eligible studies for this question.

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Gradient technique vs wash and centrifugation

It is very uncertain whether gradient technique changes clinical pregnancy rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 1.78 [0.58, 5.46]
  2 studies · 94 participants
  Very low

Gradient technique vs wash and centrifugation

The review found no eligible studies for this question.

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Gradient technique vs wash and centrifugation

It is very uncertain whether gradient technique changes multiple pregnancy rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.33 [0.01, 8.83]
  1 study · 31 participants
  Very low

Gradient technique vs wash and centrifugation

It is very uncertain whether gradient technique changes miscarriage rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 6.11 [0.27, 138.45]
  1 study · 31 participants
  Very low

Swim‐up technique vs gradient technique

It is very uncertain whether swim‐up technique changes clinical pregnancy rate per couple compared with gradient technique (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.83 [0.51, 1.35]
  4 studies · 370 participants
  Very low

Swim‐up technique vs gradient technique

It is very uncertain whether swim‐up technique changes ongoing pregnancy rate per couple compared with gradient technique (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.39 [0.19, 0.82]
  1 study · 223 participants
  Very low

Swim‐up technique vs gradient technique

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 25 participants
  Very low

Swim‐up technique vs gradient technique

It is very uncertain whether swim‐up technique changes miscarriage rate per couple compared with gradient technique (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.85 [0.28, 2.59]
  3 studies · 330 participants
  Very low

Swim‐up technique vs wash and centrifugation

The review found no eligible studies for this question.

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Swim‐up technique vs wash and centrifugation

It is very uncertain whether swim‐up technique changes clinical pregnancy rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.41 [0.15, 1.13]
  2 studies · 78 participants
  Very low

Swim‐up technique vs wash and centrifugation

The review found no eligible studies for this question.

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Swim‐up technique vs wash and centrifugation

It is very uncertain whether swim‐up technique changes multiple pregnancy rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.49 [0.02, 13.28]
  1 study · 26 participants
  Very low

Cryopreservation vs fresh embryos transfer

Cryopreservation showed no clear difference in moderate and or severe OHSS compared with fresh embryos transfer (low certainty).

• Embryo freezing for preventing ovarian hyperstimulation syndrome 2007 · Cochrane Headline outcomes only
  OR 0.12 [0.01, 2.29]
  1 study · 125 participants
  Low

Cryopreservation vs fresh embryos transfer

Cryopreservation showed no clear difference in clinical pregnancies compared with fresh embryos transfer (low certainty).

• Embryo freezing for preventing ovarian hyperstimulation syndrome 2007 · Cochrane Headline outcomes only
  OR 1.08 [0.54, 2.19]
  1 study · 125 participants
  Low

Cryopreservation vs fresh embryos transfer

Cryopreservation showed no clear difference in number of livebirths (livebirth rate) compared with fresh embryos transfer (low certainty).

• Embryo freezing for preventing ovarian hyperstimulation syndrome 2007 · Cochrane Headline outcomes only
  OR 1.03 [0.5, 2.12]
  1 study · 125 participants
  Low