Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

89 questions · 94 findings · 25 reviews

No studies found 5 · 5.3%GRADE not reported 15 · 16%Very low 27 · 28.7%Low 20 · 21.3%Moderate 17 · 18.1%High 10 · 10.6%

Summary of findings: bevacizumab vs ranibizumab

Loss of fewer than 15 letters visual acuity at one year · people with neovascular age‐related macular degeneration

Summary of findings: bevacizumab showed no clear difference in loss of fewer than 15 letters visual acuity at 1 year compared with ranibizumab (high certainty).

1 finding from 1 review

Intervention not reported

Pain: 50% reduction in headache frequency Post‐treatment Lower scores = fewer headaches · Children and adolescents with chronic pain

It is very uncertain whether the intervention changes pain: 50% reduction in headache frequency Post‐treatment Lower… (very low certainty).

1 finding from 1 review

Intervention not reported

Sleep onset latency Participant reports. Scale from 30 to 540 minutes; fewer minutes equalled better outcome; CFB and double‐blind average values included · Patients with insomnia
1 finding from 1 review
  • Eszopiclone for insomnia 2018 · Cochrane Headline outcomes only
    no estimate extracted
    9 studies · 2890 participants
    Moderate

Intervention not reported

Wake time after sleep onset Participant reports. Scale from: 30 to 540 minutes; fewer minutes equalled better outcome; CFB and double‐blind average values included · Patients with insomnia
1 finding from 1 review
  • Eszopiclone for insomnia 2018 · Cochrane Headline outcomes only
    no estimate extracted
    8 studies · 2295 participants
    Moderate

Intervention not reported

Respiratory symptoms (symptoms) Breathlessness, Cough and Sputum Scale Scale from 0 to 12. Lower score indicates fewer symptoms · individuals with stable bronchiectasis

The intervention showed no clear difference in respiratory symptoms (symptoms) Breathlessness, Cough and Sputum… (low certainty).

1 finding from 1 review

Intervention not reported

Crash outcomes measured: Killed and seriously injured (KSIs) and personal injury crashes (PICs). Across all sites KSI's decreased by 42%. This equated to about 1700 fewer KSI's per annum at these camera sites. Fixed cameras in both urban (47% redu...

The review found no eligible studies for this question.

1 finding from 1 review