Admissions at enrollment or < 24 hours (outpatients only) · patients with acute viral bronchiolitis
Epinephrine and steroid showed no clear difference in admissions at enrollment or < 24 hours (outpatients only) compared with placebo (low certainty).
1 finding from 1 review
Admissions overall up to 7 days (outpatients only) · patients with acute viral bronchiolitis
Epinephrine and steroid may leads to lower admissions overall up to 7 days (outpatients only) compared with placebo (low certainty).
1 finding from 1 review
Time to recovery · children up to 12 months old with acute bronchiolitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · children up to 12 months old with acute bronchiolitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · children up to 12 months old with acute bronchiolitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Length of hospital stay · children up to 12 months old with acute bronchiolitis
It is very uncertain whether magnesium sulphate + epinephrine changes duration of hospital stay compared with no treatment or normal saline + epinephrine (very low certainty).
1 finding from 1 review
Clinical severity score (CSS) (RDAI score; range 0 to 17; higher = poorer outcomes) measured at 0 to 24 hoursafter treatment · children up to 12 months old with acute bronchiolitis
It is very uncertain whether magnesium sulphate + epinephrine changes clinical severity score (CSS) (RDAI score; range 0 to 17; higher =… compared with no treatment or normal saline + epinephrine (very low certainty).
1 finding from 1 review
Clinical severity score (CSS) (RDAI score; range 0 to 17; higher = poorer outcomes) measured 25 to 48 hoursafter treatment · children up to 12 months old with acute bronchiolitis
It is very uncertain whether magnesium sulphate + epinephrine changes clinical severity score (CSS) (RDAI score; range 0 to 17; higher =… compared with no treatment or normal saline + epinephrine (very low certainty).
1 finding from 1 review
Hospital re‐admission within 30 days of discharge · children up to 12 months old with acute bronchiolitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Blood loss (ml) Estimated blood loss during myomectomy · women with uterine fibroids
Bupivicaine plus epinephrine showed no clear difference in blood loss (ml) Estimated blood loss during myomectomy compared with placebo to reduce blood loss during myomectomy (low certainty).
1 finding from 1 review
Blood transfusion · women with uterine fibroids
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Operating time · women with uterine fibroids
Bupivicaine plus epinephrine showed no clear difference in duration of surgery (min) Operative time compared with placebo to reduce blood loss during myomectomy (low certainty).
1 finding from 1 review
Admissions (outpatients) · children with acute bronchiolitis
2 findings from 1 review
Outcomes (2‐6 months post‐treatment) · adults with panic disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Failure to respond at endpoint (6‐12 weeks) · adults with panic disorder
Serotonin‐norepinephrine reuptake inhibitors may leads to lower failure to respond compared with placebo (low certainty).
1 finding from 1 review
Leaving the study early · adults with panic disorder
Serotonin‐norepinephrine reuptake inhibitors showed no clear difference in total number of dropouts compared with placebo (moderate certainty).
1 finding from 1 review
Failure to remit at endpoint · adults with panic disorder
Serotonin‐norepinephrine reuptake inhibitors probably leads to lower failure to remit compared with placebo (moderate certainty).
1 finding from 1 review
panic symptoms · adults with panic disorder
2 findings from 1 review
Withdrawals due to adverse events · adults with panic disorder
Serotonin‐norepinephrine reuptake inhibitors showed no clear difference in number of dropouts due to adverse effects compared with placebo (moderate certainty).
1 finding from 1 review
Need for epinephrine to treat stridor (defined as the need to use epinephrine to treat postextubation stridor) · Children up to eight years undergoing general anaesthesia
It is very uncertain whether cuffed changes need for epinephrine to treat stridor (defined as the need to use… compared with uncuffed tubes (very low certainty).
1 finding from 1 review