Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

572 questions · 579 findings · 55 reviews · Headline outcomes only

No studies found 60 · 10.4%GRADE not reported 42 · 7.3%Very low 205 · 35.4%Low 210 · 36.3%Moderate 52 · 9%High 10 · 1.7%

Summary of findings table ‐ Enteral tube feeding vs intravenous fluids

Successful insertion of intravenous fluid/enteral tube fluid at first attempt · health problem or population

Summary of findings table ‐ Enteral tube feeding probably leads to higher successful insertion of intravenous fluid/enteral tube fluid at… compared with intravenous fluids (moderate certainty).

1 finding from 1 review

Early enteral nutrition vs delayed enteral nutrition

Feed intolerance or gastrointestinal complications (as defined by the authors) · critically ill adult patients

It is very uncertain whether early enteral nutrition changes feed intolerance or gastrointestinal complications (as defined by… compared with delayed enteral nutrition (very low certainty).

1 finding from 1 review

Late parenteral nutrition vs early parenteral nutrition

Healthcare‐associated blood stream infection · critically ill term and late preterm infants

Late parenteral nutrition showed no clear difference in healthcare‐associated blood stream infection compared with early parenteral nutrition (low certainty).

1 finding from 1 review

Early enteral nutrition with supplemental parenteral nutrition (SPN) vs delayed enteral nutrition with SPN

Mortality (timing of outcome measurement unclear) · critically ill adult patients

It is very uncertain whether early enteral nutrition with supplemental parenteral nutrition (SPN) changes mortality (timing of outcome measurement unclear) compared with delayed enteral nutrition with SPN (very low certainty).

1 finding from 1 review

Early enteral nutrition with supplemental parenteral nutrition (SPN) vs delayed enteral nutrition with SPN

Feed intolerance or gastrointestinal complications (as defined by the authors) · critically ill adult patients

The review found no eligible studies for this question.

1 finding from 1 review