Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

45 questions · 51 findings · 5 reviews · Stroke

No studies found 19 · 37.3%GRADE not reported 0 · 0%Very low 9 · 17.6%Low 10 · 19.6%Moderate 8 · 15.7%High 5 · 9.8%

Intravenous thrombolytic treatment vs standard‐of‐care therapy

Symptomatic intracranial haemorrhage at · people with stroke upon awakening

Intravenous thrombolytic treatment showed no clear difference in symptomatic intracranial haemorrhage at compared with standard medical care (high certainty).

1 finding from 1 review

General anaesthesia vs non‐general anaesthesia

Functional outcomes · acute ischaemic stroke endovascular treatment (long‐term)
3 findings from 1 review

General anaesthesia vs non‐general anaesthesia

Neurological impairment · acute ischaemic stroke endovascular treatment (long‐term)

The review found no eligible studies for this question.

2 findings from 1 review

General anaesthesia vs non‐general anaesthesia

Stroke‐related mortality · acute ischaemic stroke endovascular treatment (long‐term)

General anaesthesia showed no clear difference in stroke‐related mortality compared with non‐general anaesthesia (low certainty).

2 findings from 1 review

General anaesthesia vs non‐general anaesthesia

Intracranial haemorrhage · acute ischaemic stroke endovascular treatment (long‐term)

The review found no eligible studies for this question.

2 findings from 1 review

General anaesthesia vs non‐general anaesthesia

Time to revascularisation · acute ischaemic stroke endovascular treatment (long‐term)

The review found no eligible studies for this question.

2 findings from 1 review

General anaesthesia vs non‐general anaesthesia

Target artery revascularisation (dichotomous; mTICI 2b–3) · acute ischaemic stroke endovascular treatment (long‐term)

General anaesthesia probably leads to higher target artery revascularisation (dichotomous; mTICI 2b–3) compared with non‐general anaesthesia (moderate certainty).

1 finding from 1 review