Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

332 questions · 335 findings · 55 reviews · Headline outcomes only

No studies found 77 · 23%GRADE not reported 3 · 0.9%Very low 113 · 33.7%Low 75 · 22.4%Moderate 61 · 18.2%High 6 · 1.8%

Proton pump inhibitors (PPI) vs H2RA, placebo or no treatment

Endoscopic haemostatic treatment at index endoscopy · people with upper gastrointestinal bleeding prior to endoscopic diagnosis

Proton pump inhibitor treatment probably leads to lower endoscopic haemostatic treatment at index endoscopy compared with H2RA, placebo or no treatment (moderate certainty).

1 finding from 1 review

Sinonasal debridement vs no debridement

Postoperative endoscopic appearance of the sinonasal surgical cavities: Lund‐Kennedy endoscopic score (range 1 to 10) · adult patients who underwent primary endoscopic sinus surgery, with a diagnosis of recurrent acute or chronic rhinosinusitis

Sinonasal debridement showed no clear difference in postoperative endoscopic appearance of the sinonasal surgical… compared with no debridement (low certainty).

1 finding from 1 review

Endoscopic surgery vs open surgery

Resolution of symptoms · patients with trigger finger

It is very uncertain whether endoscopic surgery changes resolution of symptoms compared with open surgery (very low certainty).

1 finding from 1 review

Endoscopic surgery vs open surgery

Participant global assessment of success Not measured · patients with trigger finger

The review found no eligible studies for this question.

1 finding from 1 review

Endoscopic surgery vs open surgery

Adverse events (infection, dysaesthesia) · patients with trigger finger

It is very uncertain whether endoscopic surgery changes adverse events (infection, dysaesthesia) compared with open surgery (very low certainty).

1 finding from 1 review

Endoscopic surgery vs open surgery

Neurovascular injury · patients with trigger finger

It is very uncertain whether endoscopic surgery changes neurovascular injury compared with open surgery (very low certainty).

1 finding from 1 review