Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

320 questions · 331 findings · 64 reviews · Headline outcomes only

No studies found 44 · 13.3%GRADE not reported 24 · 7.3%Very low 120 · 36.3%Low 90 · 27.2%Moderate 37 · 11.2%High 16 · 4.8%

Early vs delayed open or laparoscopic appendicectomy

Time away from normal activities (days) · paediatric and adult patients with appendiceal phlegmon

It is very uncertain whether early changes time away from normal activities (days) Median compared with delayed open or laparoscopic appendicectomy (very low certainty).

1 finding from 1 review

Very early discharge vs early discharge

Treatment failure; rehospitalization or adjustment of antimicrobial treatment (or both), only first episode in number of participants · children with cancer

Very early discharge showed no clear difference in treatment failure; rehospitalization or adjustment of antimicrobial… compared with early discharge (low certainty).

1 finding from 1 review

Early active flexion plus controlled passive exercise regimen vs controlled passive exercise regimen following surgery

Adverse events: participants incurring one or more adverse events · participants undergoing rehabilitation following surgery for flexor tendon injuries of the handa

It is very uncertain whether early active flexion plus controlled passive exercise regimen changes adverse events: participants incurring one or more adverse events compared with early controlled passive exercise regimen (very low certainty).

1 finding from 1 review

Summary of findings table 1: comparison of operation types: early results of needle fasciotomy vs limited fasciectomy

Early angular outcome at 6 weeks for Tubiana grade I disease (total passive extension deficit (TPED) of the MCPJ, PIPJ and DIPJ for preoperative contractures with a TPED of 0 to 45 degrees) Early angular outcome at 6 weeks for Tubiana grade II dis... · 125 hands in 121 participants with Dupuytren's disease of the fingers for early outcomes (van Rijssen 2006)
1 finding from 1 review

Total hip arthroplasty vs hemiarthroplasty

Activities of daily living · adults with displaced and undisplaced hip fractures

It is very uncertain whether total hip arthroplasty changes activities of daily living, early (within 4 months): using Katz… compared with hemiarthroplasty (very low certainty).

1 finding from 1 review

Total hip arthroplasty vs hemiarthroplasty

Functional status, early (within 4 months): using HHS (range from 0 to 100) and Johansen hip score (range from 0 to 100); higher scores indicate better function · adults with displaced and undisplaced hip fractures
1 finding from 1 review