Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

34 questions · 34 findings · 9 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 6 · 17.6%GRADE not reported 3 · 8.8%Very low 6 · 17.6%Low 13 · 38.2%Moderate 4 · 11.8%High 2 · 5.9%

Moxibustion + conventional treatment vs Western medicine

Haemoglobin (g/dL) · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment may leads to higher objective outcome measure: haemoglobin (g/L) compared with conventional medicine alone (low certainty).

1 finding from 1 review

Moxibustion + conventional treatment vs Western medicine

Objective outcome measure: platelets (× 109/L) · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment showed no clear difference in objective outcome measure: platelet (× 109/L) compared with conventional medicine alone (low certainty).

1 finding from 1 review

GnRH agonist plus chemotherapy vs chemotherapy alone

Adverse effects: hot flush · premenopausal women with malignant conditions, receiving GnRH agonist before or in parallel to chemotherapy

It is very uncertain whether gnRH agonist plus chemotherapy changes adverse effects: hot flush compared with chemotherapy alone (very low certainty).

1 finding from 1 review

GnRH agonist plus chemotherapy vs chemotherapy alone

Adverse effects: vaginal dryness · premenopausal women with malignant conditions, receiving GnRH agonist before or in parallel to chemotherapy

GnRH agonist plus chemotherapy showed no clear difference in adverse effects: vaginal dryness compared with chemotherapy alone (moderate certainty).

1 finding from 1 review

Moxibustion + conventional treatment vs Western medicine

The incidence and severity of toxicities: leukopenia (WHO grade 3 to 4) · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment showed no clear difference in the incidence and severity of toxicities: leukopenia (WHO grade 3 to… compared with conventional medicine alone (low certainty).

1 finding from 1 review

Moxibustion + conventional treatment vs Western medicine

Patient‐reported symptom: nausea/vomiting (WHO grade 3 to 4) · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment may leads to lower patient‐reported symptom: nausea/vomiting (WHO grade 3 to 4) compared with conventional medicine alone (low certainty).

1 finding from 1 review

Moxibustion + conventional treatment vs Western medicine

Diarrhoea · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment showed no clear difference in patient‐reported symptom: diarrhoea compared with conventional medicine alone (low certainty).

1 finding from 1 review