Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

135 questions · 145 findings · 44 reviews · Acute Respiratory Infections

No studies found 10 · 6.9%GRADE not reported 18 · 12.4%Very low 21 · 14.5%Low 54 · 37.2%Moderate 28 · 19.3%High 14 · 9.7%

Antihistamine‐analgesic‐decongestant vs placebo

Global evaluation · otherwise healthy adults and children with common cold symptoms

Antihistamine‐analgesic‐decongestant showed no clear difference in global evaluation: after 3 days of treatment (included children 2 to… compared with placebo (low certainty).

1 finding from 1 review

Antihistamine‐analgesic‐decongestant vs placebo

Global evaluation: after 5 days of treatment (included children 2 to 12 years old only) · otherwise healthy adults and children with common cold symptoms

Antihistamine‐analgesic‐decongestant showed no clear difference in global evaluation: after 5 days of treatment (included children 2 to… compared with placebo (low certainty).

1 finding from 1 review

Homeopathic medicinal products (individualised treatment) vs placebo or usual care

Days off work for parents · children aged up to 16 years with ARTIs

Homeopathic medicinal products (individualised treatment) showed no clear difference in days off work for parents compared with placebo or usual care (moderate certainty).

1 finding from 1 review

Point‐of‐care biomarkers (procalcitonin) for infection vs usual care

Clinical recovery · people with acute respiratory infections

The review found no eligible studies for this question.

2 findings from 1 review

Point‐of‐care biomarkers (C‐reactive protein) for infection vs usual care

Clinical recovery · people with acute respiratory infections
2 findings from 1 review