Findings

What do systematic reviews say?

25 questions · 29 findings · 3 reviews

No studies found 7 · 24.1%GRADE not reported 7 · 24.1%Very low 3 · 10.3%Low 8 · 27.6%Moderate 4 · 13.8%High 0 · 0%

Reduction in pain · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
Chainani-Wu 2007: no difference between adjunctive curcuminoids and placebo (recruitment stopped after interim analysis)
1 study · 28 participants
GRADE not reported

Adverse effects · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
Amirchaghmaghi 2016: no adverse effects recorded in either group (low-certainty)
1 study
Low

Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
Amirchaghmaghi 2016: no benefit of adjunctive curcumin for pain (low to very low certainty collectively)
1 study
GRADE not reported

Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
Amirchaghmaghi 2016: no difference in clinical resolution with vs without curcumin (very low-certainty)
1 study
Very low

Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Topical triamcinolone acetonide may leads to lower pain (mean score) compared with topical curcumin (low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
MD -0.64 [-1.19, -0.10]
2 studies · 100 participants
Low