Question · asked by 1 review

Dexamethasone + nystatin + curcumin (adjunctive) vs Dexamethasone + nystatin + placebo: Pain (mean score)

Population
People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
Intervention
Dexamethasone + nystatin + curcumin (adjunctive)
Comparison
Dexamethasone + nystatin + placebo
Outcome
Pain (mean score)

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Dexamethasone + nystatin + curcumin (adjunctive) vs Dexamethasone + nystatin + placebo
Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
Interventions for treating oral lichen planus: corticosteroid therapies (2020) · Cochrane All outcomes
Amirchaghmaghi 2016: no benefit of adjunctive curcumin for pain (low to very low certainty collectively)1 studyGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for treating oral lichen planus: corticosteroid therapies
2020 · Cochrane All outcomes
2019-02Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.