Question · asked by 1 review
Oral prednisone plus curcuminoids (adjunctive) vs Oral prednisone plus placebo: Reduction in pain
- Population
- People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
- Intervention
- Oral prednisone plus curcuminoids (adjunctive)
- Comparison
- Oral prednisone plus placebo
- Outcome
- Reduction in pain
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Oral prednisone plus curcuminoids (adjunctive) vs Oral prednisone plus placebo Reduction in pain · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment Interventions for treating oral lichen planus: corticosteroid therapies (2020) · Cochrane All outcomes | Chainani-Wu 2007: no difference between adjunctive curcuminoids and placebo (recruitment stopped after interim analysis) | 1 study · 28 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes | 2019-02 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.