Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

79 questions · 87 findings · 5 reviews · Airways

No studies found 26 · 29.9%GRADE not reported 5 · 5.7%Very low 17 · 19.5%Low 27 · 31%Moderate 8 · 9.2%High 4 · 4.6%

Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care

All‐cause mortality ‐ after 24 months Number of participants: 287(2 RCTs)

It is very uncertain whether continuous positive airway pressure (CPAP) plus best supportive care changes all‐cause mortality ‐ after 24 months Number of participants: 287(2… compared with best supportive care (very low certainty).

1 finding from 1 review

Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care

Time to life‐saving cardiovascular intervention

Continuous positive airway pressure (CPAP) plus best supportive care may leads to lower time to life‐saving cardiovascular intervention ( compared with best supportive care (low certainty).

1 finding from 1 review

CPAP with expiratory pressure relief vs fixed CPAP

Withdrawals (parallel group trials/first arm cross‐over trials) · adults with a diagnosis of sleep apnoea

CPAP with expiratory pressure relief showed no clear difference in withdrawals (parallel group trials/first arm cross‐over trials) compared with fixed CPAP (low certainty).

1 finding from 1 review

Auto‐CPAP vs fixed CPAP

Number of participants using machine for 4 or more hours per night · adults with a diagnosis of OSA

Auto‐CPAP showed no clear difference in number of participants using machine for 4 or more hours per night compared with fixed CPAP (low certainty).

1 finding from 1 review

Auto‐CPAP vs fixed CPAP

Withdrawals (parallel group trials/first arm cross‐over trials) · adults with a diagnosis of OSA

Auto‐CPAP showed no clear difference in withdrawals (parallel group trials/first arm cross‐over trials) Median compared with fixed CPAP (moderate certainty).

1 finding from 1 review