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Evidence found and GRADE certainty

96 questions · 97 findings · 12 reviews

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No studies found 32 · 33%GRADE not reported 11 · 11.3%Very low 36 · 37.1%Low 13 · 13.4%Moderate 3 · 3.1%High 2 · 2.1%

Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics

Mortality before hospital discharge · adults (aged greater than 18 years) with acute heart failure

Summary of findings table ‐ Continuous infusion of intravenous loop… showed no clear difference in all‐cause mortality (from admission to discharge) compared with bolus injection of intravenous loop diuretics (low certainty).

1 finding from 1 review

Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics

Hospital readmission · adults (aged greater than 18 years) with acute heart failure

Summary of findings table ‐ Continuous infusion of intravenous loop… showed no clear difference in readmission to hospital following discharge compared with bolus injection of intravenous loop diuretics (low certainty).

1 finding from 1 review

Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics

Acute kidney injury · adults (aged greater than 18 years) with acute heart failure

Summary of findings table ‐ Continuous infusion of intravenous loop… showed no clear difference in acute kidney injury (adverse event) (from admission to discharge) compared with bolus injection of intravenous loop diuretics (low certainty).

1 finding from 1 review

Prevention of eclampsia: IV maintenance vs a serial IV bolus regimen

Death of the baby before discharge: perinatal death · women with pre‐eclampsia

It is very uncertain whether prevention of eclampsia: maintenance regimen by continuous infusion changes death of the baby before discharge: perinatal death compared with a serial IV bolus regimen (very low certainty).

1 finding from 1 review

Prevention of eclampsia: IV maintenance vs a serial IV bolus regimen

Other neonatal morbidity: neonatal respiratory morbidity · women with pre‐eclampsia

It is very uncertain whether prevention of eclampsia: maintenance regimen by continuous infusion changes other neonatal morbidity: neonatal respiratory morbidity compared with a serial IV bolus regimen (very low certainty).

1 finding from 1 review

Continuous platinum infusion vs bolus platinum infusion

Hearing loss · children with cancer treated with platinum‐based therapy

Continuous platinum infusion showed no clear difference in hearing loss (asymptomatic and symptomatic disease according to… compared with bolus platinum infusion (low certainty).

1 finding from 1 review

Continuous platinum infusion vs bolus platinum infusion

Adverse effects: toxic death (no definition provided) · children with cancer treated with platinum‐based therapy

Continuous platinum infusion showed no clear difference in adverse effects: toxic death (no definition provided) compared with bolus platinum infusion (low certainty).

1 finding from 1 review