Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

21 questions · 33 findings · 5 reviews · Dental caries

No studies found 0 · 0%GRADE not reported 21 · 63.6%Very low 7 · 21.2%Low 4 · 12.1%Moderate 1 · 3%High 0 · 0%

Higher number of lost teeth (per one additional lost tooth) vs Fewer lost teeth (continuous, per-tooth increment)

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

Each additional lost tooth was associated with a multivariable-adjusted HR of 1.02 (95% CI 1.01 to 1.03) for ACVD-related events (13 studies, I2=75%), statistically significant; GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

3 findings from 1 review