evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

27 questions · 27 findings · 7 reviews · Skin

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 11 · 40.7%GRADE not reported 0 · 0%Very low 3 · 11.1%Low 1 · 3.7%Moderate 11 · 40.7%High 1 · 3.7%

Adalimumab weekly vs placebo

Treatment discontinuation · participants with hidradenitis suppurativa

Adalimumab weekly showed no clear difference in frequency of treatment discontinuation compared with placebo (moderate certainty).

1 finding from 1 review

Topical foscarnet vs placebo

Adverse effects during use of the preventative intervention (leading to discontinuation) · participants with recurrent herpes labialis

Topical foscarnet showed no clear difference in adverse effects during use of the preventative intervention (leading… compared with placebo (moderate certainty).

1 finding from 1 review

FAE vs MTX

Common nuisance AEs (not leading to treatment discontinuation) · psoriasis

It is very uncertain whether FAE changes common nuisance AEs (not leading to treatment discontinuation) compared with MTX (very low certainty).

1 finding from 1 review

FAE vs placebo

Common nuisance AEs (not leading to treatment discontinuation) · psoriasis

FAE probably leads to higher common nuisance AEs (not leading to treatment discontinuation) compared with placebo (moderate certainty).

1 finding from 1 review

FAE vs MTX

Withdrawals due to adverse events · psoriasis

It is very uncertain whether FAE changes AEs leading to treatment discontinuation compared with MTX (very low certainty).

1 finding from 1 review

Imiquimod 5% cream with tazarotene 0.1% gel vs Imiquimod 5% cream alone

Discontinuation of treatment due to side effects ( · participants with melanoma in situ, including lentigo maligna

Imiquimod 5% cream with tazarotene 0.1% gel showed no clear difference in secondary outcome: Discontinuation of treatment because of harms… compared with imiquimod 5% cream alone (low certainty).

1 finding from 1 review