Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,125 questions · 1,173 findings · 91 reviews · Headline outcomes only

No studies found 192 · 16.4%GRADE not reported 47 · 4%Very low 199 · 17%Low 325 · 27.7%Moderate 271 · 23.1%High 139 · 11.8%

Chemotherapy alone vs same chemotherapy plus radiotherapy

Secondary malignant neoplasms · Patients with untreated Hodgkin lymphoma (early and advanced stages)

Chemotherapy alone may leads to lower secondary malignant neoplasms compared with same chemotherapy plus radiotherapy (low certainty).

1 finding from 1 review

Chemotherapy alone vs same chemotherapy plus radiotherapy

Death · Patients with untreated Hodgkin lymphoma (early and advanced stages)

Chemotherapy alone showed no clear difference in death compared with same chemotherapy plus radiotherapy (moderate certainty).

1 finding from 1 review

Chemotherapy alone vs same chemotherapy plus radiotherapy

Progression/relapse · Patients with untreated Hodgkin lymphoma (early and advanced stages)

Chemotherapy alone showed no clear difference in progression/relapse compared with same chemotherapy plus radiotherapy (moderate certainty).

1 finding from 1 review

GnRH agonist‐antagonist cotreatment plus chemotherapy vs chemotherapy alone

Pregnancy · premenopausal women with malignant conditions, receiving GnRH agonist before or in parallel to chemotherapy

It is very uncertain whether gnRH agonist‐antagonist cotreatment plus chemotherapy changes pregnancy compared with chemotherapy alone (very low certainty).

1 finding from 1 review

GnRH agonist‐antagonist cotreatment plus chemotherapy vs chemotherapy alone

Menstruation recovery or maintenance: · premenopausal women with malignant conditions, receiving GnRH agonist before or in parallel to chemotherapy

It is very uncertain whether gnRH agonist‐antagonist cotreatment plus chemotherapy changes menstruation recovery or maintenance: compared with chemotherapy alone (very low certainty).

2 findings from 1 review

Delayed chemotherapy vs immediate chemotherapy

Nausea and vomiting · patients with asymptomatic, incurable, metastatic colorectal cancer

It is very uncertain whether delayed chemotherapy changes toxicity – nausea and vomiting compared with immediate chemotherapy (very low certainty).

1 finding from 1 review

Delayed chemotherapy vs immediate chemotherapy

Toxicity – stomatitis · patients with asymptomatic, incurable, metastatic colorectal cancer

It is very uncertain whether delayed chemotherapy changes toxicity – stomatitis compared with immediate chemotherapy (very low certainty).

1 finding from 1 review

Delayed chemotherapy vs immediate chemotherapy

Toxicity – diarrhoea · patients with asymptomatic, incurable, metastatic colorectal cancer

It is very uncertain whether delayed chemotherapy changes toxicity – diarrhoea compared with immediate chemotherapy (very low certainty).

1 finding from 1 review