Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

30 questions · 30 findings · 5 reviews

No studies found 11 · 36.7%GRADE not reported 2 · 6.7%Very low 12 · 40%Low 2 · 6.7%Moderate 3 · 10%High 0 · 0%

Summary of findings: Antithrombin III plus heparin vs heparin

Mortality attributable to hepatic veno‐occlusive disease ( · Patients undergoing stem cell transplant with malignant and non‐malignant diseases

It is very uncertain whether summary of findings: Antithrombin III plus heparin changes mortality attributable to hepatic veno‐occlusive disease ( compared with heparin alone (very low certainty).

1 finding from 1 review

Summary of findings: Antithrombin III plus heparin vs heparin

Frequency of adverse events ( · Patients undergoing stem cell transplant with malignant and non‐malignant diseases

It is very uncertain whether summary of findings: Antithrombin III plus heparin changes frequency of adverse events ( compared with heparin alone (very low certainty).

1 finding from 1 review

Intervention not reported

Mortality (subgroup analysis on bias risk) · critically ill participants

The intervention showed no clear difference in mortality (subgroup analysis on bias risk) (moderate certainty).

1 finding from 1 review

Intervention not reported

Bleeding events · critically ill participants

The intervention probably leads to higher bleeding events (moderate certainty).

1 finding from 1 review

Intervention not reported

Incidence of respiratory failure not present at admission · critically ill participants

The intervention showed no clear difference in incidence of respiratory failure not present at admission (moderate certainty).

1 finding from 1 review

Intervention not reported

Duration of mechanical ventilation · critically ill participants
1 finding from 1 review

Intervention not reported

Length of stay in hospital · critically ill participants
1 finding from 1 review

Intervention not reported

Mean length of stay in ICU · critically ill participants
1 finding from 1 review

Intervention not reported

Overall mortality among patients with severe sepsis & DIC · critically ill participants

It is very uncertain whether the intervention changes overall mortality among patients with severe sepsis & DIC (very low certainty).

1 finding from 1 review