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What do systematic reviews say?

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Evidence found and GRADE certainty

35 questions · 36 findings · 3 reviews · Infectious Diseases

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No studies found 0 · 0%GRADE not reported 1 · 2.8%Very low 5 · 13.9%Low 19 · 52.8%Moderate 11 · 30.6%High 0 · 0%

Tetracycline vs quinolones

Bacteriological failure · Adults and children with cholera diarrhoea

Tetracycline showed no clear difference in bacteriological failure compared with quinolones (low certainty).

1 finding from 1 review

Doxycycline vs quinolones

Bacteriological failure · Adults and children with cholera diarrhoea

Doxycycline may leads to higher bacteriological failure compared with quinolones (low certainty).

1 finding from 1 review

Azithromycin vs ciprofloxacin

Bacteriological failure · Adults and children with cholera diarrhoea

Azithromycin may leads to lower bacteriological failure compared with ciprofloxacin (low certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Clinical treatment failure (Persistent or worsening symptoms at the end of treatment) · patients symptomatic for NTS infection

It is very uncertain whether antibiotics changes clinical treatment failure (Persistent or worsening symptoms at the… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Diarrhoea · patients symptomatic for NTS infection

It is very uncertain whether antibiotics changes presence of diarrhoea at 2‐4 days compared with placebo or no treatment (very low certainty).

2 findings from 1 review