Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

52 questions · 54 findings · 8 reviews · Epilepsy

No studies found 4 · 7.4%GRADE not reported 5 · 9.3%Very low 14 · 25.9%Low 22 · 40.7%Moderate 9 · 16.7%High 0 · 0%

Intervention not reported

Functional outcome (number of people with disabilities) · people with postcraniotomy seizures

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

≥ 50% reduction in seizure frequency 2‐month · children with SMEI

The intervention probably leads to higher ≥ 50% reduction in seizure frequency 2‐month (moderate certainty).

1 finding from 1 review

Intervention not reported

Proportion of patients who are seizure free between 4‐40 weeks · Patients with a clinical and EEG diagnosis of BECTS

It is very uncertain whether the intervention changes proportion of patients who are seizure free between 4‐40 weeks (very low certainty).

1 finding from 1 review

Intervention not reported

Proportion of patients who discontinued treatment due to adverse events (28 weeks trial period) · Patients between five and 15 years old with a diagnosis of BECTS

The intervention showed no clear difference in proportion of patients who discontinued treatment due to adverse… (low certainty).

1 finding from 1 review

Intervention not reported

Proportion of patients who are seizure free at 3 months · Patients between three and 10 years old with a diagnosis of BECTS

The intervention probably leads to higher proportion of patients who are seizure free at 3 months (moderate certainty).

1 finding from 1 review

Intervention not reported

Proportion of patients who are seizure free at 6 months · Patients between three and 10 years old with a diagnosis of BECTS

The intervention probably leads to higher proportion of patients who are seizure free at 6 months (moderate certainty).

1 finding from 1 review