Cochrane · systematic review · CD005398

Antiepileptic drugs for the primary and secondary prevention of seizures after stroke

Chang, RS, Leung, WCY, Vassallo, M, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library

EpilepsyAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
3
No studies
3
Included studies
NR
No studies 3 · 50%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 2 · 33.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings

Population: patients with stroke
6 questions
OutcomeEffectEvidenceStatus / GRADE
Primary outcomes
no estimate extractedNRNo studies
Primary seizure prophylaxis after stroke
RR 0.65 [0.34, 1.26]2 studies · 856 participantsModerate
Secondary seizure prophylaxis after stroke
no estimate extractedNRNo studies
Secondary outcomes
no estimate extractedNRNo studies
Proportion of participants who had died or become dependent at the end of the scheduled
RR 0.97 [0.73, 1.27]2 studies · 856 participantsModerate
NIHSS from admission for SICH to 12 months
no estimate extracted1 study · 72 participantsLow