Treatment failure · neonates with possible serious bacterial infection
Comparison 2: 2 days oral amoxicillin + injectable gentamicin… showed no clear difference in treatment failure compared with 7 days injectable benzylpenicillin + injectable gentamicin (moderate certainty).
1 finding from 1 review
Adverse events · neonates with possible serious bacterial infection
1 finding from 1 review
Neonatal mortality · neonates with possible serious bacterial infection
Comparison 2: 2 days injectable benzylpenicillin + injectable… showed no clear difference in neonatal mortality compared with 7 days injectable benzylpenicillin + injectable gentamicin (low certainty).
1 finding from 1 review
Early neonatal mortality · neonates with possible serious bacterial infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Late neonatal mortality · neonates with possible serious bacterial infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Sepsis‐specific neonatal mortality · neonates with possible serious bacterial infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Treatment failure · neonates with possible serious bacterial infection
Comparison 2: 2 days injectable benzylpenicillin + injectable… showed no clear difference in treatment failure compared with 7 days injectable benzylpenicillin + injectable gentamicin (moderate certainty).
1 finding from 1 review
Adverse events · neonates with possible serious bacterial infection
Comparison 2: 2 days injectable benzylpenicillin + injectable… showed no clear difference in adverse events compared with 7 days injectable benzylpenicillin + injectable gentamicin (moderate certainty).
1 finding from 1 review
Clinical cure (bacteriological per protocol analysis) · group A streptococcal pharyngitis
It is very uncertain whether azithromycin changes clinical cure (bacteriological per protocol analysis) compared with amoxicillin (very low certainty).
1 finding from 1 review
Relapse · group A streptococcal pharyngitis
It is very uncertain whether azithromycin changes relapse (ITT analysis) compared with amoxicillin (very low certainty).
1 finding from 1 review
Relapse (bacteriological per protocol analysis) · group A streptococcal pharyngitis
It is very uncertain whether azithromycin changes relapse (bacteriological per protocol analysis) compared with amoxicillin (very low certainty).
1 finding from 1 review
Adverse events (ITT analysis) · group A streptococcal pharyngitis
It is very uncertain whether azithromycin changes adverse events (ITT analysis) compared with amoxicillin (very low certainty).
1 finding from 1 review
Clinical cure · group A streptococcal pharyngitis
It is very uncertain whether azithromycin changes clinical cure (ITT analysis) compared with amoxicillin (very low certainty).
1 finding from 1 review
Resolution of ear discharge ‐ measured at 1 to 2 weeks · adults with CSOM
It is very uncertain whether topical quinolone changes resolution of ear discharge ‐ 1 to 2 weeks compared with oral amoxicillin‐clavulanic acid combination (very low certainty).
1 finding from 1 review
Resolution of ear discharge ‐ measured after 4 weeks · adults with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life · adults with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Ear pain (otalgia) or discomfort or local irritation · adults with CSOM
1 finding from 1 review
Hearing · adults with CSOM
1 finding from 1 review
Serious complications · adults with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Suspected ototoxicity · adults with CSOM
1 finding from 1 review