Findings

What do systematic reviews say?

74 questions · 76 findings · 8 reviews · Airways

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No studies found 31 · 40.8%GRADE not reported 7 · 9.2%Very low 17 · 22.4%Low 11 · 14.5%Moderate 9 · 11.8%High 1 · 1.3%

Hypnotics vs inactive control

Quality of lifeÂ · adults with primary central sleep apnoea

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Hypnotics vs inactive control

AHI · adults with primary central sleep apnoea

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 5 participants
GRADE not reported

Hypnotics vs inactive control

All‐cause mortality · adults with primary central sleep apnoea

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Carbonic anhydrase inhibitors vs inactive control

Serious adverse events · adults with central sleep apnoea associated with heart failure

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Carbonic anhydrase inhibitors vs inactive control

Quality of sleep · adults with central sleep apnoea associated with heart failure

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Carbonic anhydrase inhibitors vs inactive control

Quality of life · adults with central sleep apnoea associated with heart failure

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Carbonic anhydrase inhibitors vs inactive control

AHI · adults with central sleep apnoea associated with heart failure

2 findings from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Very low
Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

Carbonic anhydrase inhibitors vs inactive control

All‐cause mortality · adults with central sleep apnoea associated with heart failure

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Anxiolytics vs inactive control

cAHI · adults with central sleep apnoea associated with heart failure

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
GRADE not reported

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Central AHI

The review found no eligible studies for this question.

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Cardiovascular mortality

Adaptive servo ventilation (ASV) plus best supportive care probably leads to higher cardiovascular mortality ‐ up to 80 months Number of participants:… compared with best supportive care alone or inactive control (moderate certainty).

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
RR 1.25 [1.04, 1.49]
Studies not reported
Moderate

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Serious adverse events

The review found no eligible studies for this question.

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Quality of sleep

The review found no eligible studies for this question.

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Quality of life ‐ after 48 months Number of participants: 1325(1 RCT)

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

AHI

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

All‐cause mortality ‐ up to 80 months Number of participants: 1355(2 RCTs)

Adaptive servo ventilation (ASV) plus best supportive care showed no clear difference in all‐cause mortality ‐ up to 80 months Number of participants: 1355(2… compared with best supportive care alone or inactive control (low certainty).

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
RR 0.56 [0.06, 4.93]
Studies not reported
Low

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Time to life‐saving cardiovascular intervention

The review found no eligible studies for this question.

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention vs active comparison

Quality of life ‐ CAT · COPD and at least one other long‐term condition

The review found no eligible studies for this question.

1 finding from 1 review

Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one other… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention vs active comparison

Exacerbations · COPD and at least one other long‐term condition

The review found no eligible studies for this question.

1 finding from 1 review

Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one other… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention vs active comparison

Functional status ‐ 6MWD (metres) · COPD and at least one other long‐term condition

1 finding from 1 review

Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one other… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low